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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Nov 18,2015
PLOS: PDX can be Used as an Ideal Research Model for Advanced Pancreatic Cancer
PDX models are up-and-coming and can be used to develop effective preclinical research platform for targeted therapy strategies. Now, Medicilon have the PDX models covering colon cancer,lung cancer,gastric cancer,breast cancer,liver cancer,pancreas cancer.
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PLOS: PDX can be Used as an Ideal Research Model for Advanced Pancreatic Cancer
Nov 18,2015
Break Up Anthrax Attacks, Sequence the Pieces
A strong dose of gamma-irradiation—the standing defense against weaponized anthrax—is so good at breaking apart anthrax DNA that it could complicate forensic analysis, the next step in responding to a bioterror attack. Forensic analysis has the difficult job of reading the subtle genomic signatures of weaponized anthrax and other bioterror agents, which are hard toRead more
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Nov 17,2015
New Enzyme Discovered for Sustaining Telomere Length
    In the early years of molecular biology research, scientists studying chromosomal structure and composition noticed that the terminal ends of chromosomes, called telomeres, would gradually become shorter with each successive round of cellular replication. This process would continue until the chromosome reached a certain length, ultimately becoming unstable and causing the cell to die. Conversely,Read more
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Nov 17,2015
Scientists ID Genetic Factors that Influence Body Weight and Neurological Disorders
Many neurological disorders, such as Parkinson's disease and Alzheimer's disease, are marked by impaired motor skills. In addition, growing evidence suggests there's a link between some neurodegenerative diseases and body weight.  Researchers from the U.S. Department of Energy's Lawrence Berkeley National Laboratory say they have identified genetic factors that influence motor performance and body weight.
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Scientists ID Genetic Factors that Influence Body Weight and Neurological Disorders
Nov 17,2015
Different Neurological Disorders Appear to Share Common Disease Mechanisms
    Researchers at the University of Edinburgh and an international team of colleagues report that brain disorders that cause intellectual disabilities and autism spectrum behaviors may share common defects despite having different genetic causes. Two models of intellectual disability in mice were found to have demonstrated that they share similar disease mechanisms.       The scientists discoveredRead more
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Different Neurological Disorders Appear to Share Common Disease Mechanisms
Nov 16,2015
Research Points to Development of Single Vaccine for Chikungunya and Related Viruses
    What if a single vaccine could protect people from infection by many different viruses? That concept is a step closer to reality.  For years, scientists have been on the hunt to develop vaccines that would protect against all or most strains of particularly virulent viruses such as influenza. Yet, imagine if it were possible toRead more
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Nov 16,2015
Build Better Spools, "Reel In” More DNA
Nothing beats nature's histones for tightly spooling DNA, but that hasn't stopped scientists from trying to engineer something better—at least for selected purposes. If scientists were to create custom spindles around which DNA could wrap more tightly, they would likely improve technologies for storing and transporting genetic information, delivering drugs, and building scaffolds for bioelectronics.Read more
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Nov 13,2015
Novel Stem Cell Line Avoids Risk of Introducing Transplanted Tumors
Human pluripotent stem cells (hPSC) can become any type of cell in the adult body, offering great potential in disease modeling, drug discovery and creating replacement cells for conditions ranging from cardiovascular to Alzheimer's disease.   Preparing stem cell lines is a balancing act. Stem cells should be highly potent, retaining the ability to differentiateRead more
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Novel Stem Cell Line Avoids Risk of Introducing Transplanted Tumors
Nov 13,2015
Tapping into CSF to Detect and Track Brain Tumors
    The field of liquid biopsies has exploded over the past several years with tests being conceived and validated for a large number of widely diverse cancer types. However, for a variety of reasons, liquid screens for brain tumors have been anemic—largely due to the extremely low concentrations of circulating central nervous system DNA within plasma.Read more
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Nov 12,2015
Cells May Rest, but Not Histones
    Even between rounds of cell division, during the so-called resting state, a cell stays busy, unpacking and repacking portions of the genome, accumulating epigenetic marks, and turning specific genes on and off. So, it stands to reason that all this activity would degrade histone proteins, the genome's packing material, and that histone proteins would beRead more
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