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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Feb 25,2016
The 2015 edition of the Chinese Pharmacopoeia Chemical Drugs (APIs and Preparations) Stability Research Technical Guidelines
1. Overview The stability of a drug substance or preparation refers to its ability to maintain physical, chemical, biological and microbiological properties. Stability research is based on the systematic research and understanding of APIs or preparations and their production processes. The quality characteristics of APIs or preparations obtained through design experiments will vary under theRead more
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The 2015 edition of the Chinese Pharmacopoeia Chemical Drugs (APIs and Preparations) Stability Research Technical Guidelines
Feb 25,2016
Innovative Method Measures Oxygen levels in 3D Cells Used for TOX Testing
A non-destructive technique that can measure the concentration and consumption of oxygen in 3D models of biological cells has been developed by Plymouth University in partnership with pharmaceutical company AstraZeneca.
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Innovative Method Measures Oxygen levels in 3D Cells Used for TOX Testing
Feb 24,2016
Cancer Immunotherapy May Improve with Identification of New Mutations
    The primary goal of cancer immunotherapy is to stimulate the human immune system to identify and destroy developing tumors. However, forcing immune cells to recognize tissues as foreign is proving to be much more difficult than researchers had hoped. However, a team of scientists at the Max Delbrück Center for Molecular Medicine (MDC) in BerlinRead more
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Cancer Immunotherapy May Improve with Identification of New Mutations
Feb 24,2016
Tumor Microenvironment Diversity Predicts Breast Cancer Outcomes
Intratumor heterogeneity, it is known, can complicate cancer treatments. Now it appears the same may be true of tumor microenvironment heterogeneity. According to a new study from the Institute of Cancer Research (ICR), London, breast cancers that develop within an "ecologically diverse” breast cancer microenvironment are particularly likely to progress and lead to death. TheRead more
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Tumor Microenvironment Diversity Predicts Breast Cancer Outcomes
Feb 23,2016
Rapidly Building Arteries That Produce Biochemical Signals
    Duke engineers have developed a technique to make artificial arteries that naturally produce biochemical signals vital to their functions. The technique is also ten times faster than current methods for tissue engineering of blood vessels.  It was used to make tiny arteries that can support 3-D micro-scale organ platforms for drug testing and may enableRead more
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Feb 23,2016
Suicide Cells in Tumor Environment Can Drive Metastasis
It's an appealing idea: Eliminate the cells that support a tumor, and maybe the tumor will, in a manner of speaking, come tumbling down. But what if the tumor remains standing? Even worse, what if the tumor is soon accompanied by spreading metastasis?     Such unexpected developments were in fact observed in a study conducted byRead more
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Suicide Cells in Tumor Environment Can Drive Metastasis
Feb 22,2016
Gene Drive Seen as Promising Way to Attack Spread of Mosquito Borne Diseases
    Scientists from Virginia Tech report that using genetic engineering to change female mosquito embryos into males might be an effective way to combat the increasing incidence of diseases like Zika, chikungunya, and dengue. The team describes its gene drive approach in Trends in Parasitology.     Specifically, the researchers discuss how recent breakthroughs in CRISPR-Cas9 gene editingRead more
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Gene Drive Seen as Promising Way to Attack Spread of Mosquito Borne Diseases
Feb 22,2016
Scientists Discover Bird Blood Cell Which Destroys Fatal Fungal Infection
    Scientists have discovered that a specialized white blood cell found in birds can destroy a potentially fatal fungal infection which affects more than one million people every year.     Cryptococcus neoformans is a fungus that causes fatal infections in those with a weakened immune system. It is one of the most dangerous infections of individuals with AIDS andRead more
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Feb 19,2016
Genome Studies Can Help Identify Lifestyle Risks For Diseases
    A type of study commonly used to pinpoint genetic variants associated with diseases can also be used to identify the lifestyle predictors that increase the risk of a disease – something that is often overlooked in genetic studies.     Genome wide association studies (GWAS) scan the entire genome in order to pinpoint genetic variants associated withRead more
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Feb 19,2016
Vaccine Against Designer Opioid Drug Abuse
    With the use of synthetic opioid "designer drugs” on the rise, scientists have developed a vaccine to curb addiction and even prevent fatal overdoses.      In preclinical tests, the vaccine was found to prevent the synthetic opioid fentanyl – a painkiller 50 to 500 times more potent than morphine – which some drug dealers now useRead more
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Vaccine Against Designer Opioid Drug Abuse
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