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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Mar 09,2016
Blood Test May Reveal Early Signs of Skin Cancer Relapse
    Skin cancer patients with advanced melanoma can take a sigh of relief. A new blood test developed by a team of researchers predicts the chances of relapse in patients.     Scientists from the Cancer Research UK Manchester Institute studied the DNA shed by tumors into the bloodstream (circulating tumor DNA) in blood samples from seven advancedRead more
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Mar 09,2016
NAS Urges Rapid Learning System to Accelerate Personalized Medicine
    More rigor, insists the National Academy of Sciences (NAS), must be shown by practically everyone who is working on biomarker tests for molecularly targeted therapies. Through a report announced on March 4, "Biomarker Tests for Molecularly Targeted Therapies: Key to Unlocking Precision Medicine,” the NAS is calling for "common evidentiary standards” and better coordination ofRead more
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Mar 08,2016
Aim Immuno-Oncology at Trunk Antigens, Not Branch Antigens
    For all its genetic diversity, a tumor may yet display some common elements, antigens that reflect the tumor's early mutational history. If these common elements could be identified, they could be used to target practically all of the tumor's cells for destruction, and not just tumor cells that happen to display a relatively uncommon antigenRead more
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Mar 08,2016
Rare Respiratory Disease Gene Carriers Actually Have Increased Lung Function
    New research has revealed the healthy carriers of a gene that causes a rare respiratory disease are taller and larger than average, with greater respiratory capacity.  Scientists from the University of Bristol report that rare respiratory disease gene carriers actually have increased lung function.     The disease, alpha1-antitrypsin deficiency (AATD) can result in severely reduced lungRead more
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Mar 07,2016
New Kind of Stem Cell Discovered
    Scientists at Michigan State University have discovered a new kind of stem cell, one that could lead to advances in regenerative medicine as well as offer new ways to study birth defects and other reproductive problems.     “Other scientists may have seen these cells before, but they were considered to be defective, or cancer-like,” said Parenti,Read more
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Mar 07,2016
Ancient Viral Invaders In Our DNA Help Fight Today Infections
    About eight percent of our DNA is viral in origin: remnants of ancient battles between infectious viruses and our ancestors. These so-called endogenous viruses are often perceived as a mere oddity with no clear biological significance. But a new study by scientists at the University of Utah, School of Medicine shows that evolution has repurposedRead more
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Ancient Viral Invaders In Our DNA Help Fight Today Infections
Mar 04,2016
Advanced Immunotherapeutic Method Shows Promise against Brain Cancer
    Scientists from KU Leuven in Belgium say they have shown that next-generation cell-based immunotherapy may offer new hope in the fight against brain cancer.     Cell-based immunotherapy involves the injection of a therapeutic anticancer vaccine that stimulates the patient’s immune system to attack the tumor. Thus far, the results of this type of immunotherapy have beenRead more
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Mar 04,2016
Broken Down Proteins vs Truncated Proteoforms
    If you see a shorter version of a protein, don't be too quick to dismiss it as a nonfunctional degradation product. It might be a shiny, new proteoform, an alternative version of a larger protein. The proteoform might even be more stable than the full-length protein. Although proteoforms may arise naturally as cells respond toRead more
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Broken Down Proteins vs Truncated Proteoforms
Mar 03,2016
New Approach May Prevent and Reverse Fat Related Chronic Disease
    Researchers believe their work has led to a potential new weight control method that involves manipulating the production of fat cells at their source. Their study ("De Novo Generation of Adipocytes from Circulating Progenitor Cells in Mouse and Human Adipose Tissue”), published in the FASEB Journal, shows that at least some human fat cells areRead more
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New Approach May Prevent and Reverse Fat Related Chronic Disease
Mar 03,2016
Study Links Normal Stem Cells To Aggressive Prostate Cancer
    A study that revealed new findings about prostate cells may point to future strategies for treating aggressive and therapy-resistant forms of prostate cancer.     The study proved that the prostate basal cell layer contains adult stem cells, which possess a unique gene expression profile resembling the deadliest form of prostate cancer. The research was ledRead more
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Study Links Normal Stem Cells To Aggressive Prostate Cancer