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GEM Models
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HomeservicesPreclinical ResearchPharmacology & PharmacodynamicsTumor ModelsGEM Models

GEM Models

Genetically engineered mouse (GEM) models are widely used and have proved to be a powerful tool to improve drug discovery processes. Using transgenic technology, extra DNA that encodes the gene of interest can be integrated into the mouse genome; using knockout or knock-in technology, specific regions of the mouse genome can be selectively deleted or modified.
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  • Genetically engineered mouse (GEM) models are widely used and have proved to be a powerful tool in drug discovery processes. 
    GEM models have become an invaluable tool for validating targets, identifying pharmacodynamic markers of drug action, detecting toxicity, and evaluating safety. Improvements in technologies and the development of new GEMs are expected to guide future applications of these models to drug discovery and preclinical trials.
  • Cell Line
    PD-1CTLA-4PD-1 & CTLA-4
Relevant laboratories
  • caliper
  • IVIS-Lumina-III-In-Vivo-Imaging-System
  • Frozen section
  • BD-LSRFortessa
  • operating room(outside)
  • pathological section
  • animal breeding room
  • BD-FACSCelesta
Relevant articles
Xenograft Models Orthotopic Cancer Models Syngeneic Mouse Models Humanized Mouse Models GEM Models PDX Model
Stock Code
688202

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Address: 20 Maguire Road, Suite 103, Lexington, MA 02421(America)

Tel: +1(781)535-1428(U.S.)

Address: Allia Future Business Centre Kings Hedges Road Cambridge CB4 2HY, UK

Tel: 0044 7790 816 954 (Europe)

Email: marketing@medicilon.com

  

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Tel: +82 70-8269-5849

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Postcode: 201299

Tel: +86 (21) 5859-1500 (main line)

Fax: +86 (21) 5859-6369

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