Synthetic Chemistry

Services

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  Carbohydrate Chemistry
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  Isotope-labeled Internal Standards Synthesis
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  02
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  Fluorescence Probes Synthesis
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  03
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  Peptide Synthesis
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  04

Service

• Synthesis of high-quality compounds from milligram to kilogram
  Synthesis of reagents, intermediates, building blocks, reference compounds, metabolites, and impurities
• Scaling up Compound Production to Non-GMP Level
• Custom chemical synthesis
  Delivering molecules with a completely new structureSynthesis of positive control compounds and molecular probesSynthesis of special reagents, intermediates, and molecular fragments Preparation of API or related substances Synthesis of standard substancesDesign and preparation of impurities or metabolitesSynthesis of stable isotope internal standards Delivery of SIL internal standardsSynthesis of tritiated compounds Synthesis and resolution of chiral compounds Analytical support Delivery of the product analysis report Expertise: chiral drugs, heterocyclic chemistry, carbohydrate chemistry, nucleoside chemistry, peptide chemistry and antibody-drug conjugation (ADC)
• Scale up
  Scaling-up synthesis and process optimization of preclinical candidate compoundsSynthesis of high-quality kilogram-level samplesResearching synthesis technologies for target compounds

Featured Platform

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  PROTACs Drug Synthesis Service

  PROTAC Service Scope

  PROTACs ChemistryPROTACs in vitro EvaluationPROTACs in vivo Evaluation
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  ADC Drugs Synthesis Service

  Medicilon can provide:

  ADC lab with OEB4/5 Isolator5 mg, 50 mg, 500 mg antibody level conjugation servicesExperimental cycle time : 2-4 weeksQC: SEC、HIC、LC-MS/MS etcDAR: 2-8
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  Nucleic Acid Drugs Synthesis Service

  R&D Capabilities

  Synthesis

  Nucleotide monomerOligonucleotideDelivery systemOligonucleotide coupling

  Modification

  SugarNucleobaseBackboneDelivery system

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