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Other Disease Models

Other Disease Models

Medicilon offers various effective animal models, including customized ones, based on clients' needs. Typical models include those for full-thickness skin trauma, pressure ulcers, and spontaneous hypertension with rats/mice and SHR as subjects. Further, Medicilon also offers non-human primates for pharmacology studies, such as using monkeys for cell therapy for Type-1 diabetes; and mini-pig for analgesic effect evaluation.
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DiseaseTypeSpecies
Kidney injury and failure                  Acute renal failure (Cisplatin induction)Rat
Rhabdomyolysis-induced acute kidney injury (RIAKI)  modelMouse
Renal ischemia-reperfusion  modelRat
Chronic renal failure  induced by 5/6 NephrectomyRat
Chronic renal failure  induced by AdenineRat
Diabetic renal failureZDF Rat,db/db Mouse
Renal fibrosis modelRat
Skin Healing                    Full-thickness skin trauma modelMouse/Rat
Diabetic foot ulcer modeldb/db Mouse
Standardized Scalding Burn ModelMouse/Rat
DiseaseModelSpecies
LeukopeniaLeukopenia model (Cyclophosphamide  induction)Mouse/Rat
Leukopenia model (Cytarabine  induction)Rat
Leukopenia model (Adriamycin  induction)Rat
Leukopenia model (Cisplatin  induction)Rat
Prostatic DiseasesTracheal goblet cell  staining countsMouse/Rat
Prostatic hyperplasia model (Castration)Mouse/Rat
Prostatic hyperplasia induced by AndrogenMouse/Rat
Nonbacterial prostatitisRat
Respiratory system                    Expelling phlegm test  (phenol red excretion method)Mouse
Tracheal goblet cell  staining countsRat
Sexual dysfunctionErectile function test in normal ratRat
Erectile function test in castrated ratRat
Sexual behavior test experiment (Back climbing experiment)Rat
Gynecological disease                    Mammary hyperplasia modelRat
Uterine fibroid modelRat
Endometriosis modelMouse/Rat
Hyperthyreosis                    Secondary hyperthyroidism modelMouse/Rat
SepsisSepsis model (LPS induction)Mouse
Sepsis model (CLP induction)Mouse
Ocular diseaseGlaucoma ModelRat
Choroidal  Neovascularization (CNV) ModelMouse/Monkey
Retinal  Neovascularization (RNV) ModelRabbit
Alkali Burn of Cornea  ModelRat/Rabbit
Dry AMD ModelMouse
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