Custom synthesis projects are tailored precisely to the customer's requirements for the compound, whether in small quantities (typically milligrams to 100 grams) or medium to large quantities (typically 100 grams to kilograms). These drug-like substances include drug reference compounds, lead compounds and their derivatives, combinatorial chemical templates, and other drug-like compounds. We deliver custom synthesis products in a timely and efficient manner.
Fee For Service (FFS)
The fees for the FFS model depend on parameters such as the specific experiment type, method and number of compounds to be tested.
Customization of needs
Timely completion of synthesis from small-scale (milligrams to hundred-grams) to medium-large scale quantities (hundred-grams to kilograms)
Synthesis of various target compounds
These include drug reference compounds, lead compounds and their derivatives, combinatorial chemical templates and other drug-like compounds with or without references.
Efficient team performance parameters
FFS on-time delivery rate
> 80%
Chemical reaction success rate
> 85%
Compound delivered per FTE each week
> 1
Number of reactions completed by each scientific researcher each week
> 12
The Medicilon Chemistry Department collaborates with renowned pharmaceutical companies globally to complete custom synthesis, compound library construction, target compound screening, compound structure and function optimization. Our customers include GSK, ROCHE, J&J , Genentech, Biogen, GILEAD, Takeda, Hengrui, Simcere, Jemincare, Chia Tai Tianqing Pharmaceuticals, etc .
Synthesis of reagents, intermediates, building blocks, reference compounds, metabolites, and impurities
Synthesis of Reference Compounds
Synthesis of customer-specific structure compounds
Preparation of APIs or related substances
Synthesis of standard substances
Synthesis design and preparation of impurities or metabolites
Synthesis of stable isotope internal standards
Synthesis of tritiated compounds
Synthesis and resolution of chiral compounds
Scale-up synthesis and process optimization of preclinical candidate compounds
Synthesis of high-quality kilogram-level samples
Research on target compound synthesis technology