Carbohydrate Chemistry

Carbohydrate synthesis

• Carbohydrates are vital organic compounds with diverse biological activities and applications. They play an important role in biological growth and development, immune response, signal transduction and other life processes. Carbohydrate compounds and modifications are not only used as drugs, but also serve as essential components in targeted drug delivery systems. Types of carbohydrate compounds include monosaccharides, oligosaccharides, polysaccharides, glycoconjugates (such as glycolipids, glycopeptides and glycoproteins), etc.
  Carbohydrate compounds originate from natural and synthetic sources. Natural sources encompass polysaccharides derived from microorganisms such as plants and fungi. Synthetic carbohydrate drugs are chemically modified versions of natural carbohydrate structures, including semi-synthetic carbohydrate drugs, fully synthetic glycosides, oligosaccharides, and glycoconjugate compounds. Enzymatic and chemical synthesis methods are playing an increasingly important role in the production of carbohydrate compounds.

Sugar modifications

• Medicilon specializes in the chemical synthesis and modification of nucleic acid drugs, which includes modifying ribose, bases, backbones, and delivery systems.

  

  

  

Laboratory equipment

• Medicilon is equipped with advanced instruments, including NMR (Nuclear Magnetic Resonance), HPLC (High-Performance Liquid Chromatography), SFC (Supercritical Fluid Chromatography), MS directional preparative HPLC, microwave reactor, DSC (Differential Scanning Calorimetry), TGA(Thermogravimetric Analysis), ICP-MS((Inductively coupled plasma-mass spectrometry), etc.

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