Carbohydrate Chemistry

All organisms are composed of four types of biological macromolecules: carbohydrates, lipids, nucleic acids, and proteins, as well as water and inorganic ions. Carbohydrates are the most widely distributed type of biomolecules in nature and represent the third type of biological macromolecules with significant biological importance, following proteins and nucleic acids. Carbohydrates serve as the primary source of energy and play a central role in material circulation. They also function as essential structural skeleton components, maintaining and supporting cell morphology and structure.

Carbohydrate synthesis

Carbohydrates are vital organic compounds with diverse biological activities and applications. They play an important role in biological growth and development, immune response, signal transduction and other life processes. Carbohydrate compounds and modifications are not only used as drugs, but also serve as essential components in targeted drug delivery systems. Types of carbohydrate compounds include monosaccharides, oligosaccharides, polysaccharides, glycoconjugates (such as glycolipids, glycopeptides and glycoproteins), etc.
Carbohydrate compounds originate from natural and synthetic sources. Natural sources encompass polysaccharides derived from microorganisms such as plants and fungi. Synthetic carbohydrate drugs are chemically modified versions of natural carbohydrate structures, including semi-synthetic carbohydrate drugs, fully synthetic glycosides, oligosaccharides, and glycoconjugate compounds. Enzymatic and chemical synthesis methods are playing an increasingly important role in the production of carbohydrate compounds.

Sugar modifications

Medicilon specializes in the chemical synthesis and modification of nucleic acid drugs, which includes modifying ribose, bases, backbones, and delivery systems.

Laboratory equipment

Medicilon is equipped with advanced instruments, including NMR (Nuclear Magnetic Resonance), HPLC (High-Performance Liquid Chromatography), SFC (Supercritical Fluid Chromatography), MS directional preparative HPLC, microwave reactor, DSC (Differential Scanning Calorimetry), TGA(Thermogravimetric Analysis), ICP-MS((Inductively coupled plasma-mass spectrometry), etc.

Relevant articles

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