Xenograft Models

We can provide various xenograft models to test the effectiveness of drugs according to our clients' requirements. Typical diseases include head and neck cancer, lung cancer, breast cancer, gastric cancer and pancreatic cancer, with mice, rats and hamsters as test subjects. We are committed to providing clients with mature orthotopic models for evaluating the in vivo efficacy of ADC, completing the modeling and feeding of model animals in an AAALAC-accredited environment, and relevant pharmacodynamic evaluation experiments standards of a GLP level.

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Xenograft Models

Cancer Type	Cell Lines
Brain Cancer	CHP-212, LN-229, U-87 MG, U-118, U-251 MG
Breast Cancer	BT474, DU4475, HCC1569, HCC1954, HCC70, HCC1806, JIMT-1, MCF7, MDA-MB-231, MDA-MB-436, MDA-MB-468, MX-1, SUM 149PT, ZR-75-1,
Cervix	Hela, SiHa
Colon Cancer	COLO 205, DLD-1, HCT-8, HCT-116, HCT-15, HT-29, KM12-luc, LIM-1215, LoVo, Ls174T, NCI-H716, NCI-H508, RKO, SW48, SW480, SW620, SW837
Endometrium	AN3 CA, HEC-1-A, HEC-1-B, KLE, RL95-2
Esophageal	KYSE-520
Fibrosarcoma/Soft Tissue	HT-1080
Gastric	Hs 746T, NCI-N87, MKN-45, SNU-16, NUGC-4
Head and Neck	CAL-27, Detroit562, FaDu, TT
Leukemia	CCRF-CEM, HEL, HL-60, Jurkat E6.1, JVM-3, Kasumi-1, K-562, MOLM-13, MOLM-16, MOLT-3, MOLT-4, MV-4-11, OCI-AML-3, TF-1a, THP-1, U-937
Liver Cancer	HCCLM3, Hep G2, HuH-7.
Lung Cancer	A427, A549, Calu-1, Calu-3, Calu-6, DMS114, EBC-1,HCC827, MSTO-211H, NCI-H69, NCI-H292, NCI-H358, NCI-H460, NCI-H520, NCI-H522, NCI-H526, NCI-H727, NCI-H820, NCI-H838, NCI-H1299, NCI-H1373, NCI-H1568, NCI-H1581, NCI-H1650, NCI-H1703,NCI-H1975, NCI-H2122, NCI-H2228, NCI-H3122, NCI-H3255,PC9
Lymphoma	Daudi, DB,DOHH2,HH,JeKo-1, Karpas299, MAVER-1, Mino, OCI-LY10, OCI-LY19, Raji, RL, SR, SU-DHL-1, SU-DHL-2, SU-DHL-4, SU-DHL-6, TMD-8, WSU DLCL2
Melanoma	A375, C32, SK-MEL-5
Myeloma	MM.1R, MM.1S, NCI-H929, OPM-2, RPMI-8226
Osteosarcoma	SJSA-1
Ovary	A2780, PA-1,OVCAR-3, OVCAR-8, SK-OV-3
Pancreatic	AsPC-1, Bx PC-3, Capan-1, Capan-2, CFPAC-1, HPAC, HPAF-II, Mia PaCa-2, PANC-1, SU.86.86, SW1990
Prostate	22RV1, DU145, LnCap, LNCaP-F877L mut, PC-3, Vcap
Renal	786-O, A498, ACHN, OS-RC-2
Skin	A-431
Urinary bladder Cancer	5637, HT1376, RT4, UM-UC-3

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Xenograft Models Orthotopic Cancer Models Syngeneic Mouse Models Humanized Mouse Models GEM Models PDX Model