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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Mar 26,2018
Gut Microbiome Promotes Pancreatic Cancer Progression
Understanding the appropriate balance of "good” bacteria within the intestinal tract has been the focus of much ongoing research for a number of years. Links between gut dysbiosis and the onset of disease are continually being established with the hope that therapeutic interventions may be developed soon to halt disease progression. Now, investigators at theRead more
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Gut Microbiome Promotes Pancreatic Cancer Progression
Mar 23,2018
Newly Created Life Form Stably Straddles Bacteria/Archaea Divide
Bacteria and Archaea are two of the three domains of life. Both must have evolved from the putative Last Universal Common Ancestor (LUCA). One hypothesis is that this happened because the cell membrane in LUCA was an unstable mixture of lipids. The LUCA departed long ago, taking its evolutionary secrets to the grave or –Read more
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Newly Created Life Form Stably Straddles Bacteria/Archaea Divide
Mar 23,2018
Parkinson's Gene Initiates Disease Outside of the Brain
Until very recently, Parkinson's had been thought a disease that starts in the brain, destroying motion centers and resulting in the tremors and loss of movement. New study ("Mutant LRRK2 Mediates Peripheral and Central Immune Responses Leading to Neurodegeneration In Vivo”) published in the journal Brain, shows the most common Parkinson's gene mutation may changeRead more
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Parkinson's Gene Initiates Disease Outside of the Brain
Mar 22,2018
Extreme Morning Sickness Genes Identified
Morning sickness is not an uncommon condition associated with pregnancy for most women. However, in a small percentage of women (up to 2%), an extreme form of morning sickness called hyperemesis gravidarum (HG) can present as much more than temporary discomfort, putting both mother and fetus at grave risk. Now, a new study led byRead more
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Mar 22,2018
Self-Assembling Lipid–Polypeptide Biomaterials Follow Heat Cues
Synthetic biomaterials based on peptides and proteins have lacked the versatility of their natural counterparts. The problem: Unlike the natural biomaterials, the synthetic biomaterials miss out, by and large, on the power of post-translational modification (PTM). A new kind of synthetic biomaterial, however, exploits PTM to accomplish temperature-triggered, hierarchical self-assembly. If biomaterials with these capabilitiesRead more
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Self-Assembling Lipid–Polypeptide Biomaterials Follow Heat Cues
Mar 21,2018
Nanofiber Dressings Promote Skin Regeneration and Wound Healing
With military conflicts continuing to rage on in many regions of the globe, understanding how tissues regenerate and heal is an area of research that has come to the forefront in recent years. Additionally, as one of the largest segments of the population move into their six and seventh decades, advanced healthcare initiatives focused onRead more
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Mar 21,2018
Could Chronic Fatigue Syndrome Be a Thyroid Hormone Deficiency?
Idiopathic diseases remain a thorn in both physicians’ and patient's sides from a diagnostic and therapeutic perspective. For instance, diagnosis of chronic fatigue syndrome (CFS) – an idiopathic disorder marked by lengthy spells of weakness, fatigue, and depression – is predominantly based on symptoms and on ruling out any underlying medical condition, rather than onRead more
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Mar 20,2018
Artificial Sweetener May Worsen Crohn's Symptoms
The war over the benefits and negative effects of artificial sweeteners continues to rage on as researchers from Case Western Reserve University School of Medicine (CWRUSM) have found that the artificial sweetener sucralose (Splenda) worsened gut inflammation in mice with the Crohn's-like disease but had no substantive effect on those without the condition. Findings fromRead more
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Artificial Sweetener May Worsen Crohn's Symptoms
Mar 20,2018
Single-Cell Analysis for a Penny a Profile
Partitioning is expensive, but barcoding is cheap – that's the idea behind a new technique for single-cell analysis. By dispensing with fancy cell sorters, custom microfluidics, and microwells, and introducing budget-friendly combinatorial barcoding, this new technique promises to democratize single-cell transcriptomics. The new low-cost technique, which is called split pool ligation-based transcriptome sequencing (SPLit-seq), wasRead more
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Single-Cell Analysis for a Penny a Profile
Mar 19,2018
Nanospears May Revolutionize Gene Therapy
Researchers say they have developed a new method utilizes microscopic splinter-like structures called “nanospears” for the targeted delivery of biomolecules, such as genes straight to patient cells. These magnetically guided nanostructures could enable gene therapies that are safer, faster, and more cost-effective, according to the scientists.   The study ("Precision-Guided Nanospears for Targeted and High-ThroughputRead more
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