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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Apr 02,2018
Students Achieve Poorer Grades When Classes Don’t Sync with Biological Clocks
Might it be possible to blame your college grades on whether you are a natural night owl or an early bird? Possibly to some extent, according to the results of a two year study involving nearly 15,000 students. The study, by the University of California at Berkeley's Benjamin Smarr, Ph.D., and Northeastern Illinois University's AaronRead more
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Students Achieve Poorer Grades When Classes Don’t Sync with Biological Clocks
Mar 30,2018
Recovery from Stroke and Spinal Injury Aided by Gene Deletion
In response to injury, cells typically go to work trying to repair the damage. While this healing process is amazingly effective for many tissue types, for various neuronal injuries the repair process is either extremely slow or nonexistent.   However now, a new study from investigators at the University of Texas Southwestern's O’Donnell Brain InstituteRead more
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Mar 30,2018
Antibiotic Use Increases Risk of Severe Viral Disease in Mice
People infected with West Nile virus can show a wide range of disease. Some develop life-threatening brain infections. Others show no signs of infection at all. One reason for the different outcomes may lie in the community of microbes that populate their intestinal tracts.   Antibiotics won't resolve a viral infection. And their misuse mayRead more
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Mar 29,2018
Single-Cell RNA-Seq Used to Start Creation of Malaria Cell Atlas
In 2017, the global death toll from malaria was almost half a million people and over 200 million stricken with the parasitic infection. With rampant drug resistance continuing to spread, a greater understanding of the molecular mechanisms that govern the malaria parasite's life cycle is paramount to developing improved therapies and prophylaxes.   New single-cellRead more
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Mar 29,2018
CRISPR Adapted to Prevent Unwanted Mutations
Scientists at the Wyss Institute for Biologically Inspired Engineering have adapted the CRISPR/Cas9 genome-editing system into a genome surveillance tool that acts as a "mutation prevention system” to identify and cut out DNA sequences that carry single point mutations in individual cells. When tested on Escherichia coli strains both in vitro and in the mouseRead more
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CRISPR Adapted to Prevent Unwanted Mutations
Mar 28,2018
Hungry Mice Feel Less Pain
Different behaviors are often studied in isolation, leaving a lot of unanswered questions about how the brain processes needs and prioritizes behaviors to ensure survival. Now, researchers have shown that pain and hunger interact in complex ways in mice: extreme hunger suppresses less-urgent inflammatory pain, so that the mice are willing to go find food,Read more
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Mar 28,2018
Drug Prevents Cancer by Targeting Both Tumor Cells and the Tumor Microenvironment
Researchers at Michigan State University say they are testing a drug that may stop a gene associated with obesity from triggering breast and lung cancer, as well as prevent these cancers from growing. Their findings are based on two studies ("Chemoprevention of Preclinical Breast and Lung Cancer with the Bromodomain Inhibitor I-BET 762”) and ("A BETRead more
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Drug Prevents Cancer by Targeting Both Tumor Cells and the Tumor Microenvironment
Mar 27,2018
Hand Soap Ingredient Could Be Basis for Potent Antimalarial Drugs
Cheap, stable, and easily produced compounds have been the basis of antimalarial drug development for more than half a century. However, with drug resistance continuing to rise, identifying targets that impede essential metabolic pathways at multiple times during the parasite's life cycle is a vital approach to drug design. Now, a new study led byRead more
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Hand Soap Ingredient Could Be Basis for Potent Antimalarial Drugs
Mar 27,2018
Optogenetics Used for First Time for Industrial Chemical Production
Researchers at Princeton University have used light to control genetically modified Saccharomyces cerevisiae yeast – optogenetic control – and to increase its output of commercially valuable chemicals.  The results offer scientists a powerful new tool to probe and understand the inner working of cells, according to José L. Avalos, Ph.D., an assistant professor of chemical andRead more
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Mar 26,2018
Mutations in Noncoding DNA Linked to Neurodevelopmental Disorders
Pathogenic de novo mutations in coding DNA have been implicated in neurodevelopmental disorders such as developmental brain dysfunction, which can lead to impaired learning and language. In fact, according to one estimate, 42% of patients suffering these disorders carry mutations in genes that encode proteins. But it has been unclear how many patients, including patientsRead more
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