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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
May 04,2018
Tumors Shrink, or Grow, Depending on Drug Receptor-Receptor Effect
Though inhibited by a drug, a cancer-promoting cell receptor may stage a comeback, becoming part of a receptor–receptor pair that signals cancer cells to proliferate, should growth factors be present. This undesirable teamwork, which was uncovered by scientists at the Francis Crick Institute, may explain why lapatinib failed clinical trials as a standalone drug againstRead more
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Tumors Shrink, or Grow, Depending on Drug Receptor-Receptor Effect
May 04,2018
A Peanut Allergy Test That Is Both Safe and Accurate
Peanuts are the most common cause of fatal food-induced anaphylaxis, or severe allergic reaction, and allergy cases among children have risen sharply in recent years. Britain's Food Standards Agency estimates up to one in 55 children have a peanut allergy. Canada's estimates are similar: 1 in 50 children, according to Food Allergy Canada.   NutRead more
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May 03,2018
Increasing Eye Cells’ Ability to Process Misfolded Proteins May Prevent Retinal Degeneration
Researchers at Duke University believe they have developed an approach to treat retinal conditions (including retinitis pigmentosa), all of which create misfolded proteins that cells in the eye cannot process. The scientists have shown that boosting the cells' ability to process misfolded proteins could keep them from aggregating inside the cell. They devised and testedRead more
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Increasing Eye Cells’ Ability to Process Misfolded Proteins May Prevent Retinal Degeneration
May 03,2018
New Insights into the Origins of Mutations in Cancer
The link between cancer mutations and DNA repair mechanisms has been well established. However, the specific origins of the mutation in these essential pathways have remained enigmatic. Now, researchers at the European Bioinformatics Institute (EMBL-EBI), the University of Dundee, and the Wellcome Sanger Institute have used human and worm data to explore the mutational causesRead more
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New Insights into the Origins of Mutations in Cancer
May 02,2018
Brown Fat Helps Exercisers Feel the Burn
Exercise causes many body tissues to undergo beneficial adaptations that contribute to improved metabolic health. Studies headed by a team at Ohio State University Wexner Medical Center now indicate that some of these beneficial effects may be mediated, at least in part, by a circulating lipid hormone, or lipokine, which is released by brown fatRead more
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May 02,2018
Antibiotic-Snacking Bacteria Could Help Tackle Environmental Contamination
Antibiotics can be lifesaving for people suffering from serious bacterial infections such as pneumonia and meningitis. The drugs are lethal to bacteria — but some bacteria fight back by developing resistance to antibiotics, and a few not only resist the onslaught, but turn the lethal drugs into food. Bacterial resistance to antibiotics is a growingRead more
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Antibiotic-Snacking Bacteria Could Help Tackle Environmental Contamination
May 01,2018
44 Genetic Risk Factors For Major Depression Identified
A global research consortium has identified 44 genetic variants that are risk factors for major depression – including 30 that are newly discovered – essentially mapping out the genetic basis of the mental health disorder affecting an estimated 300 million people worldwide.   The Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium hasRead more
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44 Genetic Risk Factors For Major Depression Identified
May 01,2018
Anticancer Virotherapy May Be Better If Backed by Natural Killer Overkill
They did the math, and then they checked their work – not on paper or in a computer program, but in preclinical tests – to confirm that their immunotherapy proposal added up. The proposal, offered by scientists based at UTHealth, the University of Texas Health Science Center at Houston, was that oncolytic viruses and externallyRead more
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Anticancer Virotherapy May Be Better If Backed by Natural Killer Overkill
Apr 30,2018
Employing Zika as a Cancer Killing Tool
The mosquito-borne virus Zika ignited fears around the world more than two years ago due to its link to children born with the brain malformation known as microcephaly. But a handful of cancer researchers see potential in exploiting the Zika virus (ZIKV) ability to infect the brain.
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Employing Zika as a Cancer Killing Tool
Apr 30,2018
Common Anticholinergics Linked with Dementia Even When Taken 20 Years before Diagnosis
The largest and most detailed study of the long-term impact of anticholinergic drugs, a class of drugs commonly prescribed in the United States and United Kingdom as antidepressants and incontinence medications, has found that their use is associated with increased risk of dementia, even when taken 20 years before diagnosis of cognitive impairment. Results fromRead more
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Common Anticholinergics Linked with Dementia Even When Taken 20 Years before Diagnosis
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