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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
May 11,2018
Gut Microbiota Species May Protect against Typhoid
Scientists at the University of Maryland, School of Medicine (UMSOM) have for the first time found evidence that the presence of a key species in the human gut microbiome is associated with protection from infection with typhoid fever. If the research is borne out, it could offer an exciting new way to reduce intestinal infectionsRead more
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May 11,2018
Experimental Drug Switches Off Hunger in Patients with Genetic Obesity
Obesity can be caused by mutations in the leptin receptor (LEPR) gene, causing extreme hunger that starts within the first months of life and leads to obesity during early childhood. A trial in three individuals who carry different LEPR gene mutations has now shown that a peptide drug called setmelanotide, which activates the melanocortin 4Read more
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Experimental Drug Switches Off Hunger in Patients with Genetic Obesity
May 10,2018
Working Night Shift Clashes with Day-Shift Gene Expression
Working the night shift is not a prospect that a whole lot of people relish, but that doesn't stop the positions from being filled. Statistics indicate that there were about 1.7 million Australians doing some kind of shift work as part of their main occupation in 2015, with 204,000 regularly working night and evening shiftsRead more
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May 10,2018
Human Gut Microbiome Can Predict Cholera Outbreaks with AI Assistance
Before artificial intelligence (AI) becomes sentient and seeks to destroy all humans, advanced computer systems can be utilized in various ways to help thwart potential outbreaks of deadly infectious diseases. This is exactly what a team of investigators from Duke University, Massachusetts General Hospital, and the International Centre for Diarrheal Disease Research in Dhaka, Bangladesh,Read more
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May 09,2018
Lung Cancer Biomarker Discovery Raises Hopes for Early Detection
Lung cancer is one of the most common cancers in the world. It is a leading cause of cancer death in men and women in the United States. Cigarette smoking causes most lung cancers. The more cigarettes you smoke per day and the earlier you started smoking, the greater your risk of lung cancer. HighRead more
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Lung Cancer Biomarker Discovery Raises Hopes for Early Detection
May 09,2018
CRISPR's MAGESTIC Evolution Makes Gene Editing More Precise
How far we can understand the extent to which our genes directly affect cell, tissue, and organ function depends on our ability to precisely modify the genetic code and analyze the consequences of those modifications. CRISPR, for clustered regularly interspaced short palindromic repeats, technology has revolutionized our ability to carry out gene editing, but theRead more
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CRISPR's MAGESTIC Evolution Makes Gene Editing More Precise
May 08,2018
Protein in Breast Cancer Found to Be Essential for Metastasis
One in eight women will be diagnosed with breast cancer in her lifetime, and one in 30 is expected to die from it. Thus, understanding the underlying molecular mechanisms that cause breast tumors to become metastatic is critical for improved therapies and patient outcomes. Now, investigators at the Montreal Clinical Research Institute (IRCM) and UniversityRead more
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Protein in Breast Cancer Found to Be Essential for Metastasis
May 08,2018
Malaria’s Essential Genetic Repertoire Revealed
As one of the deadliest organisms on the planet, the malaria protozoan parasite, in particular Plasmodium falciparum, owes much of its pathogenicity to its unique genomic makeup. This parasite species has a genome that is overwhelmingly skewed toward A-T base pairs (>80%), often making it difficult to study and intractable to basic molecular biological techniques.Read more
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May 07,2018
DNA Knot Study Could Help Improve Genome Sequencing Accuracy
Just like any long polymer chain, DNA tends to form knots. Using technology that allows them to stretch DNA molecules and image the behavior of these knots, MIT researchers have discovered, for the first time, the factors that determine whether a knot moves along the strand or "jams” in place.   The findings could helpRead more
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May 07,2018
Adult Stem Cells Get a Boost from Fasting
As people age, their intestinal stem cells begin to lose their ability to regenerate. These stem cells are the source for all new intestinal cells, so this decline can make it more difficult to recover from gastrointestinal infections or other conditions that affect the intestine.   A calorie-restricted diet is often said to enhance longevity.Read more
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Adult Stem Cells Get a Boost from Fasting