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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
May 18,2018
New Way to Stimulate Cellular Recycling Process
Brown University researchers studying the biology of aging have demonstrated a new strategy for stimulating autophagy, the process by which cells rebuild themselves by recycling their own worn-out parts.   In a study ("Nuclear Export Inhibition Enhances HLH-30/TFEB Activity, Autophagy, and Lifespan”), published in Cell Reports, the team shows that the approach increased the lifespans of wormsRead more
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May 17,2018
Smelly Biomarkers Accurately Predict Malaria Infections
With close to 50% of the world's population living in areas endemic to malaria and almost half a million malaria deaths per year, identifying asymptomatic carriers of this parasitic infection is a critical factor for lowering disease transmission rates. However, standard tests often miss identifying carriers, especially when parasitemias are low. Moreover, while DNA testsRead more
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Smelly Biomarkers Accurately Predict Malaria Infections
May 17,2018
Alzheimer’s Disease Linked to Loss of Epigenetic Protection
An international team of researchers has linked a gene known as peptidase M20-domain-containing protein 1 (PM20D1) with Alzheimer's disease (AD) in humans. An analysis of genetic and epigenetic study data, combined with data from human tissue samples and subsequent experiments in mouse models, indicated that increased levels of PM20D1 in the brain have a protectiveRead more
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Alzheimer’s Disease Linked to Loss of Epigenetic Protection
May 16,2018
Cancer Screen with Spheroids Shows Promise Therapeutically
Scientists from The Scripps Research Institute say they have developed a new method to screen for possible cancer drugs. The technique makes use of tiny, three-dimensional, ball-like aggregates of cells called spheroids, which can be used to interrogate hundreds or even thousands of compounds rapidly using high-throughput screening (HTS).   Using this approach, the teamRead more
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May 16,2018
Optical Tweezing Lasers Sculpt Artificial Cell Membranes
Made-to-order cells may soon transition from the realm of science fiction to the reality of science and medicine, as researchers from Imperial College London and Loughborough University have demonstrated a new level of complexity with artificial cells by arranging them into basic tissue structures with diverse types of connectivity. The scientists have used lasers toRead more
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May 15,2018
Novel Protein Analysis Tool Could Boost Quality and Accuracy of Medical Diagnosis
A new protein analysis tool developed at the University at Buffalo (UB) could vastly increase the speed and precision with which disease and drug effects are analyzed.  Called IonStar, it is the first to provide near-perfect accuracy when quantifying and comparing the abundance of proteins in the bodies of people who are healthy and ill,Read more
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Novel Protein Analysis Tool Could Boost Quality and Accuracy of Medical Diagnosis
May 15,2018
Flesh-Eating Bacteria Contained by Botox and Peptide Antagonist
Bacterial infections are generally a mild annoyance to the average person, often ranging from mild malaise to high fever. Yet, in rare cases, garden-variety bacterial infections, such as those that lead to strep throat, can go extremely awry and lead to massive tissue damage. For instance, the bacterium, known as Streptococcus pyogenes, is also theRead more
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Flesh-Eating Bacteria Contained by Botox and Peptide Antagonist
May 15,2018
Medicilon Promotes the Development of New Drugs!
Shanghai HaiHe Pharmaceutical Co., Ltd and 3D Medicines announced on April 28, the two sides reached strategic collaboration in FGFR inhibitors (code-named "HH185”) that from HaiHe Pharmaceutical and 3D Medicines have the right to start the research, production and commercialization of HH185 in mainland China, Hong Kong, Macao and Taiwan for the treatment of tumorRead more
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Medicilon Promotes the Development of New Drugs!
May 14,2018
Hepatitis B Genetic Evolution from Stone Age Uncovered
Around the world, more than 200 million people live with an infection from the hepatitis B virus, a pathogen that can reside in the human body for long stretches of time and cause serious complications, such as chronic liver disease.   Understanding the molecular origins of infectious diseases such as hepatitis B can provide valuableRead more
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May 14,2018
Cancer Drug Resistance Predicted by CRISPR Screens
Scientists at the Institute of Cancer Research (ICR) in the U.K. have harnessed CRISPR-Cas9 genome-editing technology to uncover why some tumors are resistant to poly (ADP-ribose) polymerase inhibitors (PARPi), such as olaparib and talazoparib. The studies, headed by Chris Lord, Ph.D., professor of Cancer Genomics at ICR, found that mutations in the PARP1 gene prevent theRead more
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Cancer Drug Resistance Predicted by CRISPR Screens
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