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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jun 21,2018
Breast Cancer Epigenetics Study Reveals Potential Drug Targets
Cell lineages that culminate in mammary gland development may also lead to breast cancer. Although these lineages, as well as the stem cells and progenitor cells they comprise, have been subjected to extensive study, the perturbations of these lineages that increase the risk of breast cancer have remained obscure, frustrating the search for chemoprevention drugs.Read more
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Breast Cancer Epigenetics Study Reveals Potential Drug Targets
Jun 21,2018
Aggressive Brain Cancer Can Be Driven by Tumor Suppressor
AMP-activated protein kinase (AMPK) is involved in regulating cell metabolism and is largely thought to play a suppressive role in cancer. Research by scientists at the Cincinnati Children's Cancer and Blood Diseases Institute has now indicated that the protein may represent a key driver of aggressive brain cancers, including glioblastoma (GBM). Their studies showed thatRead more
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Aggressive Brain Cancer Can Be Driven by Tumor Suppressor
Jun 20,2018
Microbiome-Lax May Relieve Constipation
So great a need for constipation relief, so few constipation remedies. If only the estimated 4 million Americans who suffer from constipation had more options, particularly since dietary interventions so often fail. Additional options, new research suggests, may finally be on their way, in the form of genetically engineered probiotics. According to researchers at theRead more
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Microbiome-Lax May Relieve Constipation
Jun 20,2018
Two Vaccines Are Better Than One for Malaria
The tenacity of the malaria parasite has all too often made it intractable to long-term therapeutic intervention. The development of parasite drug resistance is almost an inevitability, causing public health organizations to rethink treatment and prevention strategies. While vaccines would seem the most viable option toward long-term prevention and eradication, individual vaccines developed thus farRead more
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Jun 19,2018
Optogenetic Hack Advances Synthetic Morphogenesis
A living organism, says the synthetic biologist, is the output generated by a tangle of interconnected subprograms. Naturally, the synthetic biologist wants to disentangle these programs and – to the extent possible – modularize them, so that they may be plucked from their ordinary, living contexts and put to work, harnessed for applications such asRead more
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Jun 19,2018
Gut Microbes May Contribute to Depression and Anxiety in Obesity
Like everyone, people with type 2 diabetes and obesity suffer from depression and anxiety, but even more so. Work in mice by researchers in the U.S. and Japan now suggests that bacteria in the gut – the microbiome – may contribute to depressive-type behaviors in animals with diet-induced obesity (DIO). The studies, headed by researchersRead more
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Gut Microbes May Contribute to Depression and Anxiety in Obesity
Jun 18,2018
New Prostate Cancer Subtype Identified, Responsive to Immunotherapy
Researchers in the U.S. and U.K. have identified a new subtype of prostate cancer that is characterized by loss of both copies of the CDK12 gene, and which an early clinical study showed can respond to immune checkpoint inhibitor drugs that commonly aren't effective against prostate cancer.   The new tumor subtype is characterized byRead more
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Jun 18,2018
Gene Expression Map Created of Cells in Aging Brain
Researchers say they have mapped the gene expression of each individual brain cell during aging in the fruit fly. Their study ("A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain”), published in Cell, could lead to new insights on the workings of the brain as it ages, according to the scientists. "The diversity of cellRead more
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Gene Expression Map Created of Cells in Aging Brain
Jun 15,2018
Fast-Acting Vaccine and Probiotic Combat Cholera in Animals
One of the most terrifying things about cholera is its lethal speed. A victim can consume contaminated food or water, come down with diarrhea a day later and, if untreated, be dead a day after that – having inadvertently spread the microorganism to friends, neighbors and family members in the meantime. New probiotic and vaccine-basedRead more
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Jun 15,2018
Parkinson's Protein Transition Provides Insight into Disease Progression
Researchers say they have completed a detailed brain cell analysis that has helped them to uncover new mechanisms thought to underlie Parkinson's disease. They believe their study ("α-Synuclein Oligomers Interact with ATP Synthase and Open the Permeability Transition Pore in Parkinson's Disease”), published in Nature Communications, adds to the growing understanding of the causes of Parkinson's andRead more
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Parkinson's Protein Transition Provides Insight into Disease Progression
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