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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jun 28,2018
Brain Cancer Gets the Polio Treatment
Immunotherapy has enjoyed much-deserved adulations over the past several years, as scientists have proven that the basic biology is sound and drugs developed to modulate the human immune system contain an immense therapeutic value. Yet, aggressive cancers such as those residing within the brain have been particularly difficult to treat and require some "outside theRead more
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Brain Cancer Gets the Polio Treatment
Jun 27,2018
Stretchy Tissue Molecule Decoded
The stretchiness that allows living tissues to expand, contract, stretch, and bend throughout a lifetime is the result of a protein molecule called tropoelastin. Remarkably, this molecule can be stretched to eight times its length and always returns back to its original size.   Now, for the first time, scientists say they have decoded theRead more
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Stretchy Tissue Molecule Decoded
Jun 27,2018
Oxygen-Starved Cancer Cells Languish without Aspartate
Deep inside tumors, where oxygen is scarce, cancer cells are reduced to scrounging metabolites from their surroundings. A particularly valuable metabolite happens to be aspartate. If oxygen-starved cancer cells can pick up aspartate, report scientists based at Rockefeller University, they survive, grow, and proliferate despite their suffocating conditions. The hunger for aspartate, the Rockefeller UniversityRead more
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Oxygen-Starved Cancer Cells Languish without Aspartate
Jun 26,2018
Breast Cancer Risk Reduced in Younger Women with Higher Body Fat
Contrary to the body of evidence that has been accrued over the years showing that obesity increases the risk of developing breast cancer in postmenopausal women, a new study from investigators at the University of North Carolina Lineberger Comprehensive Cancer Center found the opposite to be true for premenopausal women – higher body fat wasRead more
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Jun 26,2018
Gut Microbiome Understanding Insight Facilitated by New Platform
Researchers say they have taken a step closer to better understanding how the gut microbiome is formed, changes over time, and is affected by disturbances like antibiotics.   Published in Molecular Systems Biology, a study ("Deciphering Microbial Interactions in Synthetic Human Gut Microbiome Communities”) by a team from the University of Wisconsin-Madison and the University ofRead more
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Jun 25,2018
Old TB Vaccine Improves Diabetes Blood Sugar Levels
Type 1 diabetes, which is typically diagnosed in kids and young adults, is characterized by the pancreas not making insulin or making very little, according to the federal Centers for Disease Control and Prevention. Insulin is a hormone that allows blood sugar to enter the body’s cells and be used for energy.   Investigators atRead more
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Jun 25,2018
Cancer Metastasis Hobbled by New Compound
Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body. Researchers at Northwestern University, Chicago, and Oregon Health & Science University (OHSU) in Portland, have developed a small-molecule drug that can stop the movement of cancer cells and soRead more
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Cancer Metastasis Hobbled by New Compound
Jun 23,2018
Pharmacokinetic test / toxicokinetic test
Pharmacokinetic research is to reveal the dynamic changes of the drug in the body through the research methods of animal in vivo, external and human in vitro, obtain the basic kinetic parameters of the drug, clarify the process and characteristics of drug absorption, distribution, metabolism and excretion. Pharmaceutics, pharmacodynamics, safety evaluation research and clinical researchRead more
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Pharmacokinetic test / toxicokinetic test
Jun 22,2018
Inherited Pancreatic Cancer Gene Mutations Discovered in Patients with No Family History
Only about 10% of all pancreatic cancer cases are associated with individuals that have a prior family history. Investigators at the Mayo Clinic have now uncovered clinical evidence suggesting that current testing guidelines miss genetic predisposition to cancer in the remaining 90% of pancreatic cancer patients. The researchers identified six genes containing mutations that mayRead more
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Jun 22,2018
Alzheimer's Disease May Be Triggered by Herpes Virus
A fringe theory about the origins of Alzheimer's disease – that latent viral infections can sometimes trigger its emergence – has gotten perhaps its most significant bit of support yet. A study has found evidence that certain viruses are not only more common in the brains of people with Alzheimer's, but that they play aRead more
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Alzheimer's Disease May Be Triggered by Herpes Virus