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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jul 06,2018
Artificial Bimolecular Networks Open Door to Sophisticated Diagnostic Testing
Scientists at Caltech say they have developed an artificial neural network made out of DNA that can solve a basic machine learning problem: correctly identifying handwritten numbers.
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Artificial Bimolecular Networks Open Door to Sophisticated Diagnostic Testing
Jul 05,2018
Stem Cells Renew Heart Function in Primates with Cardiac Failure
Researchers at the University of Washington, Seattle, have used human embryonic stem cell-derived cardiomyocytes (hESC-CMs) to restore heart function in macaque monkeys with heart failure. The researchers hope that their achievement could pave the way for development of a similar treatment for human patients. The macaque studies showed that the transplanted hESC-CMs developed into ventricularRead more
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Jul 05,2018
Biological Switch Can Control Genome Editing
A biological switch that reliably turns protein expression on at will have been invented by University of Bath and Cardiff University scientists. The switch enables control of genome editing tools that might one day regulate cascades of desired genetic changes through entire populations. The team points out that this new switching method should work for anyRead more
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Jul 03,2018
Computing Method Used to Track Cancer Spread
Tracing and predicting the course that metastatic cancers take through the body may shed light on cellular changes that lead to metastasis. Metastatic disease causes about 90% of cancer deaths from solid tumors – masses of cells that grow in organs such as the breast, prostate, or colon. Understanding the drivers of metastasis could leadRead more
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Computing Method Used to Track Cancer Spread
Jul 03,2018
Autism Genetic Complexity Comes to Light
Genes located in a large chromosomal aberration associated with autism interact with each other to modulate the variable symptoms of the disease, according to new research.  A Penn State-led team tested the role of these genes individually and in tandem by reducing the amount of the genes expressed in a fruit fly model.   TheirRead more
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Jul 02,2018
Approved Anti-Cancer Drugs Reveal New Target: Non-Coding RNAs
Scientists at The Scripps Research Institute and the California Institute for Biomedical Research (CALIBR) have found that some types of small-molecule drugs, including marketed anticancer drugs, may work in part by binding to disease-related noncoding RNAs. Their discovery could open up new avenues of research for developing small-molecule drugs against what are otherwise considered undruggable.
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Approved Anti-Cancer Drugs Reveal New Target: Non-Coding RNAs
Jul 02,2018
Alzheimer's Drugs Targeting Tau May Actually Exacerbate Disease
A new study by researchers from Drexel University College of Medicine reverses the popular scientific dogma that the protein tau stabilizes microtubules within brain cells. Their work ("Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile Domains”), which appears in Current Biology, suggests just the opposite. Tau's actual role in theRead more
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Alzheimer's Drugs Targeting Tau May Actually Exacerbate Disease
Jun 29,2018
Key Protein Mediating Inflammatory Response Discovered
Inflammation has always been a double-edged sword, providing critical action that helps heal wounds or thwart infections, in addition to damaging healthy cells and tissues due to a disproportionate response. Understanding the regulatory mechanisms that control the balance between positive and negative inflammation could open new drug discovery avenues for a variety of diseases andRead more
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Key Protein Mediating Inflammatory Response Discovered
Jun 29,2018
Prostate Cancer Treatment Response Activated by Skin Disease Immunotherapy
Scientists in the U.K., Switzerland, and Italy have shown how a type of immunotherapy that is undergoing trials for treating psoriasis also renders advanced prostate cancer responsive to hormone therapy. The researchers' studies in human tissue and in a mouse model found that castration-resistant prostate cancer (CRCP) is driven by interleukin-23 (IL-23) produced by immuneRead more
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Prostate Cancer Treatment Response Activated by Skin Disease Immunotherapy
Jun 28,2018
Cancer Cells Resist Dying through Telomerase Regulation
Cancer becomes more common as people get older, but scientists are still searching for answers about why this happens.  However now, investigators at the Hollings Cancer Center, part of the Medical University of South Carolina, found that human lung cancer cells resist dying by controlling parts of the aging process. Findings from the new studyRead more
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Cancer Cells Resist Dying through Telomerase Regulation
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