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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jul 27,2018
Parkinson's Symptoms Associated with Contact Sports
In recent years awareness about the neurological risks associated with playing contact sports has risen exponentially. This increased mindfulness stems from the mounting evidence that repetitive head impacts from contact sports and other exposures are associated with the neurodegenerative disease chronic traumatic encephalopathy (CTE) and dementia.
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Parkinson's Symptoms Associated with Contact Sports
Jul 26,2018
Viral Microbiome Changes Could Be an Underlying Cause of IBD
It's relatively commonplace these days to associate the term microbiome only with bacterial communities. Yet, viruses infinitely outnumber bacteria, especially within the mammalian gut. As such, researchers at North Carolina State University, the University of Texas Southwestern Medical Center, and the University of Colorado wanted to know if the viral communities within the intestinal tractRead more
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Viral Microbiome Changes Could Be an Underlying Cause of IBD
Jul 26,2018
HIV Transmission Blocked by Often Overlooked Class of Antibody
The mammalian immune system produces a range of antibody types in order to protect the host from the daily onslaught of foreign invaders. These various antibody classes typically have well-defined roles and are often temporally produced in response to antigens and often isolated to various tissue types.   Immunoglobulin M (IgM) is usually the firstRead more
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Jul 25,2018
Wrinkles and Hair Loss Reversed through Mitochondrial Restoration
Skin wrinkles and hair loss are two of the most commonly bemoaned signs of aging, but a team at the University of Alabama at Birmingham (UAB) has now demonstrated how both of these telltale features of passing years can be reversed, at least in a mouse model. Studies in experimental mice by UAB professor ofRead more
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Wrinkles and Hair Loss Reversed through Mitochondrial Restoration
Jul 25,2018
HIV Drug Reduces Neurodegenerative Disease Pathology in Fruit Flies
Scientists at the University of Texas Health San Antonio have linked unwanted activation of transposable elements, or "jumping genes,” with nerve cell death in neurodegenerative tauopathies such as Alzheimer's disease.  Their studies in fruit flies found that toxic tau protein deposition that is characteristic of tauopathies is associated with the disruption of epigenetic mechanisms thatRead more
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HIV Drug Reduces Neurodegenerative Disease Pathology in Fruit Flies
Jul 24,2018
Overcoming Resistance to a Standard Chemotherapy Drug
Despite being studied for decades, the chemotherapy drug cisplatin is revealing new aspects of how it works.  Scientists at Winship Cancer Institute of Emory University have identified an enzyme responsible for making tumors and cancer cell lines resistant to cisplatin, along with an experimental drug that targets that enzyme. Their study ("MAST1 Drives Cisplatin Resistance.
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Overcoming Resistance to a Standard Chemotherapy Drug
Jul 24,2018
Genome-Tailored Diets May Be Premature
Individual genomic profiles promise the ultimate in personalized medical care – which includes dietary guidance. In fact, as popular news sources have reported, personalized nutrition testing and services are already trying to read genomes as if they were menus. But it may be too early to book a reservation at Chez Genome. According to scientistsRead more
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Jul 23,2018
When "Good” Cholesterol Goes "Bad”
Just as beauty is in the eye of the beholder, the terms “good” and “bad” have always been somewhat subjective. For cardiovascular health, physicians regularly monitor the levels of "good cholesterol” (high-density lipoproteins or HDL) and "bad cholesterol” (low-density lipoproteins or LDL). Traditionally, cardiovascular risk is assessed by measuring levels of HDL and LDL.  Read more
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Jul 23,2018
Mixed mRNA Tails Less Easily Docked
mRNA is a delicate molecule with an important function; it brings genetic information contained in the DNA out of the nucleus to produce proteins. When a gene is transcribed into messenger RNA (mRNA), the mRNA is equipped with a tail, that acts like a shield against pre-mature degradation. For mRNA molecules, degradation is inevitable, butRead more
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Jul 20,2018
High Vinculin Levels Help Keep Aging Fruit Fly Hearts Young
Our cells tend to lose their shape as we grow older, contributing to many of the effects we experience as aging. This poses particular problems for the heart, where aging can disrupt the protein network within muscle cells that move blood around the body. A new discovery in how heart muscles maintain their shape inRead more
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