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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Aug 02,2018
Cancer Immunotherapy Looks to Exploit Hair Loss Gene
For many patients diagnosed with cancer, hair loss is often an inevitable consequence of various therapeutic interventions. Yet, what if instead of worrying about trying to abolish the negative hair loss side-effect of cancer therapies, scientists were able to exploit hair-loss genetics to improve the new wave of immunotherapy compounds. Well, that is exactly whatRead more
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Cancer Immunotherapy Looks to Exploit Hair Loss Gene
Aug 02,2018
Cancer Cells Feel Acid’s Sting
Cancer cells are known to acidify their environment and, consequently, the interior of the cells themselves is alkalised. In principle, this deregulation should hinder the development and proliferation of these cells. However, exactly the opposite happens in cancer. Scientists from the Institute for Research in Biomedicine (IRB Barcelona), University of Maryland, and the MOFFIT report that cancerRead more
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Cancer Cells Feel Acid’s Sting
Aug 01,2018
Hair Loss Caused by Fatty Diet Reversed
In a series of experiments with mice, scientists have used an experimental compound that blocks production of glycosphingolipids (GSLs) to successfully reverse hair loss, hair whitening and skin inflammation linked by previous studies to human diets heavy in fat and cholesterol. What is D-PDMP?
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Hair Loss Caused by Fatty Diet Reversed
Aug 01,2018
Genetic Hotspot Studies Could Lead to Better Understanding of Cancer
Scientists from Indiana University (IU) say they have identified "hotspots” in DNA where the risk for genetic mutations is significantly elevated. These mutations arise because "typos” can occur as DNA replicated during cellular division.  A recent analysis, which found that random mistakes in DNA play a large role in many cancer types, underscores the need to understandRead more
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Genetic Hotspot Studies Could Lead to Better Understanding of Cancer
Jul 31,2018
Bacteria Blamed for Rapid Tooth Decay Open Wide, Genomically
The most prevalent chronic disease in both children and adults, tooth decay occurs when the good and bad bacteria in our mouth become imbalanced. The bad bacteria, Streptococcus mutans, forms a biofilm (aka tartar), then takes the sugars we eat and ferments them into acid, which decalcifies our teeth and causes cavities. But tooth decayRead more
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Jul 31,2018
Macrophage-Produced Protein Plays Essential Role in Arterial Health
Scientists at the National University of Singapore, Yong Loo Lin School of Medicine, say they have identified a population of macrophages that coat the outer walls of healthy arteries and express a protein called LYVE-1. The researchers found that when these cells were absent, arteries accumulate collagen and lose their elasticity, becoming inflexible.   The teamRead more
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Jul 30,2018
Phosphatases in Line for Target-Based Discovery
When drug developers assemble their Most Wanted lists, they may overlook the phosphatases, signaling enzymes that are notoriously hard to pick out of a lineup. Phosphatases, however, may soon find themselves the subject of intense investigation, now that scientists from the Medical Research Council (MRC) have created a platform for target-based discovery of phosphatase inhibitors.Read more
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Phosphatases in Line for Target-Based Discovery
Jul 30,2018
Cannabis Doesn't Improve COPD Exercise Endurance
Chronic obstructive pulmonary disease (COPD) is a progressive respiratory ailment, often tied to smoking, with characteristics of bronchitis and emphysema. The incurable disease remains the third biggest killer in the United States. At first blush, it would seem almost obvious that individuals with COPD did not show improvement after inhaling vaporized cannabis. However, with realRead more
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Jul 29,2018
Medicilon introduces Bio-Plex suspension chip multiple detection platform
The Bio-Plex suspension chip multiple detection platform can simultaneously detect up to 100 molecules in the same sample. Because of its good data reproducibility, it is now widely used in immunology and various disease research. Such as cardiovascular disease, tumor-specific biomarker screening, drug treatment target development, drug treatment effect evaluation, disease-related angiogenesis, metastasis, cell proliferation,Read more
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Medicilon introduces Bio-Plex suspension chip multiple detection platform
Jul 27,2018
Sperm's RNA-to-Go Expedites Embryonic Implantation
Sperm bring more than DNA to the party. They also pick up RNA on their way through the epididymis, a duct situated between the testis and the vas deferens. This RNA, it turns out, influences gene regulation in developing embryos, helping them implant in the uterus more efficiently. These findings, which emerged from a pairRead more
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Sperm's RNA-to-Go Expedites Embryonic Implantation