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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Aug 16,2018
Study Finds Genetic Basis of Common Diseases May Span Tens of Thousands of SNPs
Scientists in the U.S. and Korea have developed a statistical method for estimating the broad numbers of DNA variations that impact on different physical traits, such as height or childhood IQ, and on a wide range of diseases, from diabetes to bipolar disorder.   Their findings, derived from analyses of existing genome-wide association studies (GWAS),Read more
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Study Finds Genetic Basis of Common Diseases May Span Tens of Thousands of SNPs
Aug 16,2018
Sexual Behavior Determined by Immune Cells in the Brain
The immune system is not typically taken into consideration by neuroscientists when discussing sexual behavior in the developing brain. Yet now, a new study from investigators at The Ohio State University (OSU) may have many scientists rethinking behavioral development, as the researchers found a surprising new explanation of how young brains are shaped for sexualRead more
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Sexual Behavior Determined by Immune Cells in the Brain
Aug 15,2018
Oligonucleotide Nanostructure Targets Cancer Cells for RNA Therapy
The delivery of therapies specifically to cancer cells has always been hindered by limitations of the delivery molecules – all too often off-target effects can be detrimental to a patient's overall health. Moreover, while chemotherapies have been highly useful as targeted treatments for cancer, unwanted side effects still plague therapeutic outcomes. However now, researchers atRead more
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Aug 15,2018
Genome Sequencing Identifies Cause of Early Infantile Epileptic Encephalopathy
Early childhood seizures result from a rare disease that begins in the first months of life. Scientists at University of Utah (U of U) Health report that they have developed high-tech tools to uncover the genetic cause of early infantile epileptic encephalopathy (EIEE). Their study ("Whole-genome analysis for effective clinical diagnosis and gene discovery in earlyRead more
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Aug 14,2018
Kidney Cancer Biomarker Predicts Disease Risk and Survival
Validated diagnostic markers are key to the early detection and treatment of cancer. Moreover, if these biomarkers can be readily extracted and detected in bodily fluids, a simple, clinical diagnostic test can be developed that would be of extreme value to patients and physicians. For kidney cancer, investigators at Brigham and Women's Hospital (BWH) andRead more
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Kidney Cancer Biomarker Predicts Disease Risk and Survival
Aug 14,2018
Glaucoma May Be an Autoimmune Disease
Glaucoma, a disease that afflicts nearly 70 million people worldwide, is something of a mystery despite its prevalence. Little is known about the origins of the disease, which damages the retina and optic nerve and can lead to blindness.  While the primary risk factor for glaucoma is high intraocular pressure (IOP), the mechanisms that underpinRead more
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Aug 13,2018
Ketogenic Diet May Increase Risk of Type 2 Diabetes
One of the most popular types of weight-loss diets today is the ketogenic diet – a diet that's high in fat and low in carbohydrates. But this type of diet may be linked to an increased risk of type 2 diabetes in the first few days of the diet, new research in animals suggests.  Read more
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Ketogenic Diet May Increase Risk of Type 2 Diabetes
Aug 13,2018
Antibodies May Prove to Be Promising Therapeutics against Ebola
An international team of scientists reports that therapeutic antibodies may be the best way to stop the Ebola virus. Their study ("Systematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protection”), published in Cell, suggests new therapies should disable the Ebola virus’s infection machinery and spark the patient’s immune system toRead more
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Aug 10,2018
Transport Protein Study May Lead to New Therapies for Psychiatric Disorders
Researchers at the Columbia University Irving Medical Center (CUIMC) have found new evidence of how certain transport proteins are working at the molecular level, paving the way for new, improved drugs to treat psychiatric disorders. Their study ("The LeuT-fold neurotransmitter:sodium symporter MhsT has two substrate sites”) is published in PNAS. "Crystal structures of the neurotransmitter:sodiumRead more
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Aug 10,2018
Single-Cell Genetic Atlas of Breast Development Reveals New Cancer Targets
Scientists have recognized the relationship between normal organ development and cancer for more than 100 years. More recently, researches have begun to emphasize that the heterogeneous nature of most cancers largely contributes towards their clinical response.   Now, scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U), in collaboration withRead more
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Single-Cell Genetic Atlas of Breast Development Reveals New Cancer Targets