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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Aug 23,2018
New Subtype of Multiple Sclerosis Described
Cleveland Clinic researchers have discovered a new subtype of multiple sclerosis (MS), providing a better understanding of the individualized nature of the disease.   MS has long been characterized as a disease of the brain’s white matter, where immune cells destroy myelin. The demyelination was believed to be responsible for neuronal death that leads toRead more
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Aug 23,2018
Inflammation Regulated by Body's Internal Clock
The inflammatory response is an immensely complex mechanism that can be affected by a host of internal and external factors, but are the associated pathways regulated by the body's circadian rhythm?   New data from investigators at the Royal College of Surgeons in Ireland (RCSI) and Trinity College Dublin would suggest yes. The findings fromRead more
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Aug 22,2018
Antibiotic Class Emerges through Digestive Enzyme
Scientists in the U.S. and Italy have discovered that fragments of the stomach enzyme pepsinogen, which when activated normally help to digest proteins in our food, also have antibiotic activity that can kill food-borne and lung pathogens. The researchers, at Massachusetts Institute of Technology (MIT), and the University of Naples Federico II, used a computational-experimentalRead more
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Antibiotic Class Emerges through Digestive Enzyme
Aug 22,2018
Strawberries May Reduce Gut Inflammation
Eating your fruits and veggies every day to improve overall health need not be a chore or even unsatisfying, as investigators from the University of Massachusetts (UMass), Amherst have discovered that consuming a little less than a cup of strawberries could mitigate colonic inflammation and improve gut health.   Findings from the new study willRead more
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Aug 21,2018
Weaponizing Oxygen to Kill Infections and Disease
The life-threatening bacteria called MRSA can cripple a hospital since it spreads quickly and is resistant to treatment.  Researchers from the University of Cincinnati report that they are developing a new method to attack methicillin-resistant Staphylococcus aureus (MRSA) that does not involve antibiotics. Instead, they are using light to activate oxygen, which then wipes outRead more
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Aug 21,2018
Parkinson's Diagnosis Could Be in the Eyes of the Holder
All eyes may be on a new study from investigators at the Seoul National University Boramae Medical Center, as scientists are suggesting that a patient's eyes may be a window to the brain for people with early Parkinson's disease (PD). The new study – published recently in Neurology through an article titled "Retinal thinning associatesRead more
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Parkinson's Diagnosis Could Be in the Eyes of the Holder
Aug 20,2018
No Mitochondrial Pain, No Longevity Gain
Oxidative stress can motivate cells to live according to the Nietzschean sentiment that goes, "What does not kill us makes us stronger.” Cells, after a brief oxidant challenge, may react by pumping up their production of antioxidants, developing an enhanced antioxidant capacity, and becoming more resistant to subsequent oxidant challenges. These cellular responses, which wereRead more
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Aug 20,2018
Blind Mice See after Gene Factors Stimulate Genesis of Rod Photoreceptors
We're already familiar with the three blind mice, but we never hear about blind zebrafish. Perhaps that's because zebrafish have admirably flexible retinal stem cells called Müller glia (MG). In zebrafish, these cells can replenish damaged retinal neurons and restore vision. In mice and other mammals, however, Müller glia usually refuses to differentiate into retinalRead more
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Aug 17,2018
Zombie Gene Helps Elephants Outpace Cancer
Long ago, a "dead gene” buried in the genomes of groundhog-sized animals gained the ability to jerk back to life. The gene, called leukemia inhibitory factor 6 (LIF6), stirs when it is alerted to DNA damage. Then it expresses a protein that staggers around until it latches onto mitochondria and gnaws on them, spilling theirRead more
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Zombie Gene Helps Elephants Outpace Cancer
Aug 17,2018
HIV Biologic Drug Reduces Viral Load While Boosting Immunity
In the U.S. alone, there are over one million individuals living with HIV and 1 in 7 of them don't know they are infected. As antimicrobial resistance is a growing global public health threat, researchers are actively taking steps to minimize the emergence and spread of HIV drug resistance – as well as treating currentRead more
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