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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Sep 07,2018
How Unsaturated Fats Protect against Cardiovascular Disease Revealed
Investigators at the Keenan Research Centre for Biomedical Science (KRCBS) of St. Michael’s Hospital in Toronto have just uncovered some of the mechanisms underlying the cardioprotective effects of eating foods high in unsaturated fats.   Apolipoprotein A-IV, known as ApoA-IV, is a plasma protein. Levels of ApoA-IV increase after the digestion of foods, particularly foodsRead more
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Sep 06,2018
Thousands of Antibiotic Combinations Found to be More Effective than Predicted
Scientists have traditionally believed that combining more than two drugs to fight harmful bacteria would yield diminishing returns. The prevailing theory is that that the incremental benefits of combining three or more drugs would be too small to matter, or that the interactions among the drugs would cause their benefits to cancel one another out.Read more
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Thousands of Antibiotic Combinations Found to be More Effective than Predicted
Sep 06,2018
Copy Number Alteration Found to Be Associated with Cancer Mortality
Scientists have discovered a link between certain changes in the genome of a tumor and increased chances of death across multiple types of cancer. Their study ("Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death”), published in eLife, suggests the percentage of a tumor's genome with copy number alteration (CNA) is associatedRead more
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Copy Number Alteration Found to Be Associated with Cancer Mortality
Sep 05,2018
Sports Supplement Inhibits Growth of Drug-Resistant Breast Tumors
Scientists in the U.S. have found that a dietary supplement added to sports drinks can effectively reduce the growth of human drug-resistant HER2-positive breast cancer tumors in mice. The studies, headed by Mayo Clinic Pharmacologist Taro Hitosugi, Ph.D., found that the supplement, cyclocreatine targets mitochondrial creatine kinase 1 (MtCK1), which is involved in a mitochondrialRead more
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Sports Supplement Inhibits Growth of Drug-Resistant Breast Tumors
Sep 05,2018
Nanosponges Offer New Approach to Treatment of Rheumatoid Arthritis
Engineers at the University of California San Diego (UCSD) have developed neutrophil “nanosponges” that can safely absorb and neutralize a variety of proteins that play a role in the progression of rheumatoid arthritis. Injections of these nanosponges effectively treated severe rheumatoid arthritis in two mouse models. Administering the nanosponges early on also prevented the diseaseRead more
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Sep 04,2018
MS Drug Slows Brain Shrinkage by Nearly Half
A team led by researchers from the Cleveland Clinic's Neurological Institute reports that a promising drug slowed brain shrinkage in progressive multiple sclerosis (MS) by nearly half. Limited therapies are currently available for this disabling form of the disease, according to the scientists.     The definitive results of the Phase II trial ("Phase 2Read more
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MS Drug Slows Brain Shrinkage by Nearly Half
Sep 04,2018
Cannabis Extract Reduces Psychotic Symptoms
The antipsychotic effects of cannabidiol, a cannabis extract, are a little less mysterious now that functional magnetic resonance imaging (fMRI) has been used to reveal exactly where cannabidiol exerts its effects in the brain. Cannabidiol, scientists based at King's College London report, modulates activation in the striatum, the medial cortex, and the midbrain – threeRead more
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Aug 31,2018
Stems Cells Used as Delivery Truck for Brain Cancer Drugs
Common brain cancers in children, such as medulloblastoma, have been notoriously difficult to treat therapeutically, with traditional interventions reliant on inefficient surgical techniques to remove the bulk of the cancerous tissue. However now, new data from the University of North Carolina (UNC) Lineberger Comprehensive Cancer Center and UNC Eshelman School of Pharmacy may lead toRead more
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Stems Cells Used as Delivery Truck for Brain Cancer Drugs
Aug 31,2018
Controlling Obesity May Depend on Modifying Neurobehavioral Factors
Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to researchers at the Montreal Neurological Institute and Hospital (The Neuro). Their study ("Neurobehavioral correlates of obesity are largely heritable”), published in the Proceedings of the National Academy of Sciences, wasRead more
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Aug 30,2018
New Brain Cell Has Unique Shape, Behavior, Gene Signature
Two research teams – one focused on gene expression, the other on cell shape and behavior – converged on a previously unknown type of brain cell. Because it resembles a rose deprived of its petals, the newly discovered brain cell has been called the "rosehip neuron.” Intriguingly, it may be unique to human brains, orRead more
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