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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Sep 14,2018
Caffeine Consumption Might Help Lower Chronic Kidney Disease Mortality
Researchers report ("Caffeine consumption and mortality in chronic kidney disease: a nationally representative analysis”) in Nephrology Dialysis Transplantation that consuming more caffeine may help reduce the risk of death for people with chronic kidney disease.   The possible protective effect of caffeine might be related with effects at the vascular level as caffeine is known to promote theRead more
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Sep 13,2018
Rotavirus Study Could Lead to Development of New Treatments for Disease
Scientists have provided new insight on the mechanics of a virus that causes severe diarrhea and sickness in young children, according to a report ("Biophysical properties of single rotavirus particles account for the functions of protein shells in a multilayered virus”) published in eLife.   The study, from the Autonomous University of Madrid, Carlos III Health Institute,Read more
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Sep 13,2018
Binge Drinking Affects Male and Female Brains Differently
Binge drinking changes the pattern of gene expression in an area of the brain called the nucleus accumbens (NAc), which is linked with addiction. A new study in mice by researchers at Oregon Health & Science University, and VA Portland Health Care System has now shown that gene expression changes that occur in response toRead more
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Sep 12,2018
Vaccine-Induced T Cells Go "Sugar-Free”
Glucose is typically the primary fuel source for the vast majority of the body's cells. Moreover, when cells are under stress, they will switch from using glucose and scavenge other sources to maintain energy reserves – often extremely inefficiently.   However, a new finding surrounding how vaccine-induced T cells utilize glucose from investigators at theRead more
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Sep 12,2018
New Approach Combines Three Methods to Detect Structural Variants in Cancer Cells
Cancer cells often have mutations in their DNA that can give scientists clues about how the cancer started or which treatment may be most effective. Finding these mutations can be difficult, but a new method may offer more complete, comprehensive results.   Scientists say they have developed a new framework that can combine three existingRead more
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Sep 11,2018
Memories Strengthened through Epigenetic Mechanism
In biology, memories have always had an enigmatic quality that has often eluded researchers studying their formation and retention.   Yet now, investigators at the University of Alabama at Birmingham (UAB) have just discovered a novel mechanism that links epigenetic changes in the hippocampus of the rat brain that controls downstream regulation of translation inRead more
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Memories Strengthened through Epigenetic Mechanism
Sep 11,2018
Family Genetics Key to Severity of Autism and Other Neurodevelopmental Disorders
Techniques such as high-throughput genome sequencing have allowed scientists to identify hundreds of genetic variants that are linked with increased risk of different neurodevelopmental or neuropsychological disorders, such epilepsy, schizophrenia, intellectual disability, and autism spectrum disorder (ASD). However, two people with the same known risk variant won't necessarily present with the same symptoms.   ARead more
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Family Genetics Key to Severity of Autism and Other Neurodevelopmental Disorders
Sep 10,2018
Pouring Stem Cell Factors into Wounds Could Heal Skin Ulcers
In large patches of ulcerous skin, surviving cells prioritize inflammation and wound closure. That's what they're programmed to do. Cells, however, can be reprogrammed – as laboratory procedures have demonstrated. Now cells can also be reprogrammed in living tissue, wounded tissue, to expedite healing. No balm is necessary, unless stem cell factors may be consideredRead more
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Sep 10,2018
Excessive Daytime Sleepiness Could Be Linked to Alzheimer
Alzheimer's disease is the most common form of dementia.  It affects around 5.7 million people in US – and this number is predicted to rise.  Some estimate that, by 2050, 13.8 million US adults might be affected.  Despite its growing prevalence, treatment options are lacking and there is no cure. The exact causes are notRead more
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Sep 07,2018
Viruses Go Lytic or Latent, Based on Viral DNA Mechanics
When viral DNA is more "liquidy,” it is more easily injected into host cells – so easily, in fact, that multiple virus-carrying capsids may squeeze their DNA payloads into a host cell simultaneously. This finding is significant because it helps explain why some viral infections follow a lytic course, in which the host cell isRead more
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Viruses Go Lytic or Latent, Based on Viral DNA Mechanics