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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Sep 21,2018
Green Tea Compound Helps siRNA Slip Inside Cells
It's called a "green nanoparticle” – not because it arises in nature, but because it incorporates a metabolite, an antioxidant, that is found in green tea. The green nanoparticle's other component, a small polymer, is not so natural. It is low in toxicity, however, and it can complex with the antioxidant to form a uniqueRead more
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Sep 20,2018
Machine Learning Method Sheds Light on Cell Organization
Researchers at the Allen Institute have used machine learning to train computers to see parts of the cell the human eye cannot easily distinguish. Using 3D images of fluorescently labeled cells, the team taught computers to find structures inside living cells without fluorescent labels, using only black and white images generated by an inexpensive techniqueRead more
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Machine Learning Method Sheds Light on Cell Organization
Sep 20,2018
Some Cancer Drugs Might Be Repurposed to Treat Vascular Inflammation
G-protein-coupled receptors (GPCRs) are everywhere in our bodies. They are embedded in our cell membranes, where they act as signal transducers, allowing cells to respond to their external environments. GPCRs play a crucial role in most biological functions, including heart rate, blood pressure, vision, smell, taste and allergic responses. GPCR malfunction can lead to aRead more
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Some Cancer Drugs Might Be Repurposed to Treat Vascular Inflammation
Sep 19,2018
Shark DNA in the Water? Cue Music from Jaws
Sharks aren't any more interested in hunting people than they've ever been, but they may be cruising our coasts in larger numbers, raising the odds, however slightly, that sharks may attack surfers, ocean swimmers, and beachgoers. Nearby sharks can be tracked, offering the public some security. For example, sharks can be followed visually or taggedRead more
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Sep 19,2018
Lymphatic Vessels in Brain Provide New Route to Treat MS
Scientists at the University of Virginia (UVA) School of Medicine suggest that lymphatic vessels that clean the brain of harmful material may play a crucial role in the development and progression of multiple sclerosis. The vessels appear to carry previously unknown messages from the brain to the immune system that ultimately trigger the disease symptoms. BlockingRead more
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Sep 18,2018
Altered Levels of Neonatal Inflammatory Markers Associated with Childhood Leukemia
A new study finds that children with B-cell precursor acute lymphoblastic leukemia (ALL) have an immune profile at birth that differs from matched controls. Although the cause of ALL remains unknown, this finding lends support to the hypothesis that a dysregulated immune function in combination with certain postnatal environmental exposures leads to the development ofRead more
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Altered Levels of Neonatal Inflammatory Markers Associated with Childhood Leukemia
Sep 18,2018
Microbiome Response Can Serve as Early Warning to Nerve Gas Exposure
Researchers report that the mammalian microbiome can act as a sentinel due to its high responsiveness to exposure. Their research article ("Poisoning with Soman, an Organophosphorus Nerve Agent, Alters Fecal Bacterial Biota and Urine Metabolites: a case for Novel Signatures for Asymptomatic Nerve Agent Exposure”) appears in Applied and Environmental Microbiology.   "The experimental pathophysiology of organophosphorusRead more
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Sep 17,2018
Skin Development Finding Could Lead to Novel Therapies for Burns and Birth Defects
University of Colorado Boulder researchers have discovered a key mechanism by which skin begins to develop in embryos, shedding light on the genetic roots of birth defects like cleft palate and paving the way for development of more functional skin grafts for burn victims.   “This study maps how skin development starts, from the earliestRead more
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Sep 17,2018
Chronic Pain Gets Placebo Treatment
The phrase "never underestimate the power of the placebo” is typically used as a snarky response to symptoms that seemingly improve from therapies that have shown to have no real biological effect.   Yet now, investigators at Northwestern University's Feinberg School of Medicine believe they can reliably predict which chronic pain patients will respond toRead more
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Sep 14,2018
Common Diarrhea-Causing Bacterium Found to Produce Electricity
Researchers at the University of California (UC), Berkeley, say they have discovered that a common diarrhea-causing bacterium, Listeria monocytogenes, produces electricity using an entirely different method from known electrogenic bacteria, and that hundreds of other bacterial species use this same process.   Their study ("A flavin-based extracellular electron transfer mechanism in diverse Gram-positive bacteria”), publishedRead more
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