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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Sep 28,2018
Olfactory Ensheathing Cells May Open New Route to Glioblastoma Therapy
A special type of cell essential to the ability of olfactory neurons to regenerate may be genetically engineered to deliver anticancer therapy to glioblastomas, according to Massachusetts General Hospital (MGH) researchers who published their study ("Olfactory Ensheathing Cells: A Trojan Horse for Glioma Gene Therapy”) in the Journal of the National Cancer Institute. The team describes using olfactory ensheathingRead more
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Olfactory Ensheathing Cells May Open New Route to Glioblastoma Therapy
Sep 27,2018
Pancreatic Cancer Growth Blocked by New Drug
Pancreatic ductal adenocarcinoma, a common and aggressive type of cancer, often develops resistance to treatments such as chemotherapy. However, a new drug tested in mice may be able to eliminate the cancer's defenses. As one of the leading causes of cancer-related deaths in the U.S., pancreatic cancer represents a major threat to public health. ThisRead more
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Pancreatic Cancer Growth Blocked by New Drug
Sep 27,2018
Molecular Channel That Regulates Blood Pressure Described
Scientists report that they have visualized the three-dimensional structure of a membrane channel that's critical in controlling blood pressure. Their findings ("Structure of the human epithelial sodium channel by cryo-electron microscopy”), published in eLife, represent the first time the human epithelial sodium channel has been shown so precisely since it was first isolated and described through expression cloningRead more
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Molecular Channel That Regulates Blood Pressure Described
Sep 26,2018
Prion Disease Harms Neurons via Stress Pathway
Prions beget prions, we know, but we lack a good understanding of prion diseases. We can follow the progress of prion diseases up to a certain point – the accumulation of misfolded proteins. To press forward, we need to see exactly how prions cause neuronal degeneration, the proximate cause of the symptoms associated with prionRead more
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Prion Disease Harms Neurons via Stress Pathway
Sep 26,2018
Gene Therapy May be Effective Against Mitochondrial Diseases
Scientists say they have developed a genome editing tool for the potential treatment of mitochondrial diseases, which are serious and often fatal conditions affecting 1 in 5000 people.   The team, led by the University of Cambridge, applied an experimental gene therapy treatment in mice, and was able to successfully target and eliminate the damaged DNARead more
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Sep 25,2018
Human Egg Precursor Generated in a Dish
Infertility is something that can break any parent's heart. To not have the power of procreation is devastating and has made many marriages lose their stability.   Human pluripotent stem cells cradled by a mouse ovarian environment – a sort of living "dish” – differentiated into states that brought the cells close to becoming matureRead more
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Sep 25,2018
Drowsy Driver Blood Test Steered by RNA Biomarker
Scientists from the Sleep Research Centre at the University of Surrey say they used a machine learning algorithm to identify a subset of 68 genes to detect with 92% accuracy whether a blood sample was from a sleep-deprived or well-rested individual.   The study ("Identifying and validating blood mRNA biomarkers for acute and chronic insufficientRead more
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Sep 24,2018
Why Do Some Genes Get All the "Likes”?
A few genes achieve research stardom, whereas many, many, many others, including potentially important genes, languish in obscurity. So, why do only certain genes permanently bask in the spotlight? A big part of the reason comes down to social networking – not the newfangled social networking of Twitter and Facebook, but rather, the familiar give-and-take-and-take-and-takeRead more
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Sep 24,2018
Natural Antibiotic Shows Promise against Drug Resistant
Researchers report that a naturally occurring antibiotic, kanglemycin A, is effective against Mycobacterium tuberculosis, the bacteria that cause tuberculosis (TB), even in drug-resistant strains. The team, which used chemistry, molecular biology, microbiology, and x-ray crystallography to show how the compound maintains its activity, published its study ("Mode of Action of Kanglemycin A, an Ansamycin Natural ProductRead more
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Sep 21,2018
Scientists Discover "Noisiest” Step in the Protein Production Process
Researchers report that they have used a combination of computational and experimental methods to examine how a variety of cells produce different proteins and to measure noise, i.e., the variability in the amount of each protein they express for every step along the production process. The team discovered that for 85% of genes, the noiseRead more
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Scientists Discover "Noisiest” Step in the Protein Production Process
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