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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Oct 04,2018
Cholesterol-Related Gene Variants Impart Benefits, Point to New Drugs
From the DNA of nearly 300,000 veterans, scientists have singled out a handful of genetic mutations that not only govern levels of cholesterol, but may also inform the development and use of drugs for cardiovascular disease and diabetes, or abdominal aortic aneurysms.   The study scientists, led by a group at Stanford University School ofRead more
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Oct 04,2018
Algorithm Could Help Scientists Split a Protein and Reassemble It to Functionality
According to a team of biochemists and biophysicists it's almost impossible for proteins to be split up and reassembled on command, however the researchers claim that a computer model could be another step towards using chemical and light signals to create new medical treatments and biosensors. The team published its study ("Computational design of chemogeneticRead more
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Oct 03,2018
Protein Regulator of Glioblastoma Migration Identified
A specific protein called TEAD1 is an important regulator of tumor migration in glioblastoma, the most common brain tumor in adults, and deactivating this protein may stop tumor cells from migrating away from the main tumor mass, according to research conducted at the Icahn School of Medicine at Mount Sinai.  The data garnered through thisRead more
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Protein Regulator of Glioblastoma Migration Identified
Oct 03,2018
Major Advance Reported in Understanding Antibiotic Resistance
Scientists at the University of Montana (UM) and the University of Washington have discovered how pathogenic bacteria resist antibiotic treatment and recently published their findings in an article titled ("Entropically-driven aggregation of bacteria by host polymers promotes antibiotic tolerance in Pseudomonas aeruginosa”) in the Proceedings of the Natural Academy of Sciences. "Bacteria causing chronic infections are generally observedRead more
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Oct 02,2018
Immunotherapy Pioneers Take 2018 Nobel Prize
This year 2018, the Nobel committee has sought to recognize the enormous potential and meteoric rise in success of immunotherapy as a strategy for treating cancer. By stimulating the inherent ability of our immune system to attack tumor cells this year's Nobel Laureates have established an entirely new principle for cancer therapy.   Specifically, theRead more
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Oct 02,2018
Brain Defects Linked to Growth Factor Hormone
Investigators at the Medical University of South Carolina (MUSC) made a recent discovery that could provide crucial insights into structural changes within the brain and have a profound impact on dietary habits to improve overall brain health. The new study showed that high levels of fibroblast growth factor 23 (FGF23) were associated with structural changesRead more
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Brain Defects Linked to Growth Factor Hormone
Oct 01,2018
Novel Alzheimer's Mechanism May Have Uncovered New Treatment Strategy
The specific cause of Alzheimer's disease (AD) remains unclear and has even caused a Shakespearean-like feud among scientists with the amyloid family on one side not wanting to fraternize with the tau folks! Ok, perhaps that's bit overdramatic, but researchers often ascribe to one AD theory over the other. However now, investigators at Rutgers UniversityRead more
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Novel Alzheimer's Mechanism May Have Uncovered New Treatment Strategy
Oct 01,2018
DNA Vaccine Shows Promise for Cancer Immunotherapy
Scientists at The Wistar Institute have implemented a novel structurally designed synthetic DNA vaccine to simultaneously target multiple members of a family of proteins that are specifically overexpressed in several types of cancer. They say their approach addressed a difficult issue in cancer immunotherapy, specifically how to simultaneously drive antitumor immune responses against multiple tumorRead more
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DNA Vaccine Shows Promise for Cancer Immunotherapy
Sep 30,2018
Scientists establish a new method of ion channel drug research
On September 26, the journal Nature Communications published an online publication of the Cai Shiqing Research Group of the Institute of Neuroscience of the Chinese Academy of Sciences, the Center for Excellence in Brain Science and Intelligent Technology of the Chinese Academy of Sciences, the State Key Laboratory of Neuroscience and the Beijing Anzhen HospitalRead more
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Scientists establish a new method of ion channel drug research
Sep 28,2018
Stem Cell Discovery Could Lead to Blood Vessel Repair
Life-changing treatments for cardiovascular disease are on the horizon after scientists made a groundbreaking discovery that could enable them to grow new blodd vessels.   University College London (UCL) scientists report that a unique source of stem cells in blood helps to build blood vessels in the growing embryo. They say their study ("Erythro-myeloid progenitors contributeRead more
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