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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Oct 11,2018
Vaccine Tag Might Stop Human-Mosquito Malarial Tag
For decades, scientists have been trying to develop a vaccine that prevents mosquitoes from spreading malaria among humans.   It takes a nanoparticle, says a team of University of Buffalo (UB) scientists, to raise a transmission-blocking vaccine that will more effectively curb the spread of malaria. This nanoparticle is a liposome-based system that serves asRead more
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Oct 11,2018
Micropeptide Restores Heart Function in Mice
In heart failure, the heart is unable to pump blood effectively throughout the body. One key factor in the development of this condition is calcium dysregulation. A newly discovered molecule that may be able to address this issue could become the next therapeutic target for this heart condition. Scientists have discovered a micropeptide molecule thatRead more
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Micropeptide Restores Heart Function in Mice
Oct 10,2018
New Hippocampus Map Shows Structures and Functions in Great Detail
Curing some of the most vexing diseases first requires navigating the world's most complex structure – the human brain. So, USC scientists have created the most detailed atlas yet of the brain's memory bank. Scientists at the University of Southern California (USC) say they have created a map of the hippocampus using fluorescent tracers andRead more
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New Hippocampus Map Shows Structures and Functions in Great Detail
Oct 10,2018
Epigenetic Sequencing Using Enzymatic Detection Method
Investigators at the University of Pennsylvania's (UPenn) Perelman School of Medicine have provided a novel method for sequencing epigenetic modifications using 1,000-fold less DNA than the current gold standard technique. The UPenn researchers believe that their novel method could pave the way for better detection of cancer and other diseases in the blood. Findings fromRead more
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Oct 09,2018
Low-Dose Aspirin May Lower Ovarian Cancer Risk
Women who reported recent, regular use of low-dose aspirin (100 milligrams or less) had a 23% lower risk of developing ovarian cancer when compared with women who did not regularly take aspirin, according to new research led by Harvard T.H. Chan School of Public Health. The research team, which analyzed data from more than 200,000Read more
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Oct 09,2018
Checkpoint Inhibitor Generated by Synthetic DNA in Vivo
The cancer immunotherapy toolbox may one day make room for a new tool, the DNA-encoded monoclonal antibody (DMAb). Like conventional monoclonal antibodies, DMAbs bind to cancer checkpoint molecules, thereby releasing the brakes on immune cell activity. Unlike conventional monoclonal antibodies, DMAbs are expressed in vivo rather than being painstakingly manufactured, stored, transported, and finally administered.Read more
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Checkpoint Inhibitor Generated by Synthetic DNA in Vivo
Oct 08,2018
Unique Drug Repurposing Collection Made Available as Public Resource
Each year, millions of people worldwide suffer from potentially fatal infectious diseases that often leave survivors facing a lifetime of related health problems. But what if drugs against such diseases already existed but nobody knew it? Scientists at Calibr, a nonprofit drug discovery division of Scripps Research, have exploited an open access collection of existing,Read more
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Unique Drug Repurposing Collection Made Available as Public Resource
Oct 08,2018
Nanopore System Can Measure Metabolites Simultaneously in Biological Fluids
University of Groningen scientists, led by Associate Professor of Chemical Biology Giovanni Maglia, have designed a nanopore system that is capable of measuring different metabolites simultaneously in a variety of biological fluids, all in a matter of seconds. The electrical output signal is easily integrated into electronic devices for home diagnostics, according to the teamRead more
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Nanopore System Can Measure Metabolites Simultaneously in Biological Fluids
Oct 05,2018
Nobel in Chemistry Awarded for Directed Evolution of Enzymes and Antibodies
The 2018 Nobel Prize in Chemistry was awarded to three scientists who put evolution to work to design molecules from living organisms that eventually led to the development of cleaner biofuels and drugs for treating diseases including psoriasis.   Gregory Winter (left), Frances Arnold and George Smith   The pioneers of directed evolution recognized byRead more
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Oct 05,2018
Marijuana Use Could Be Worse for Cognitive Development in Adolescents Than Alcohol
It has been well established that the use of alcohol during adolescence can have a significant impact on cognitive functions into adulthood. However, due to drug classification and stringent regulations by governmental agencies, information about the long-term effects of marijuana use, especially by early teens, has been limited.   Yet now, a new study byRead more
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