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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Oct 18,2018
Immunotherapeutic Antibody Helps Prevent Neurodegeneration
Scientists from the Gladstone Institutes say they developed an antibody that blocks the inflammatory and oxidative activity of fibrin, which contributes to neurodegeneration in the brain, without compromising the protein’s clotting function. To come up with a precise and highly effective antibody, the researchers focused on targeting only a small region of the fibrin protein thatRead more
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Oct 18,2018
Cancer Can Change Neutrophils' Behavior Influencing Them to Support Tumor Growth
Lung cancer is the leading cause of cancer death among men and women. According to the American Cancer Society, the disease kills more people each year than colon, breast, and prostate cancers combined. Therefore, uncovering the precursors and behaviors of lung cancer remains a major target among scientists working to improve cancer outcomes. For moreRead more
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Cancer Can Change Neutrophils' Behavior Influencing Them to Support Tumor Growth
Oct 17,2018
Crohn's Subtype Accurately Predicted through miRNA Molecule
Crohn's disease (CD), a chronic inflammatory condition of the intestinal tract, has emerged as a global disease, with rates steadily increasing over the last 50 years. Experts have long suspected that CD likely represents a collection of related but slightly different disorders, but until now it has not been possible to predict accurately which subtypeRead more
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Oct 17,2018
Alzheimer's Progression Tracked through Antioxidant Levels
The idea that antioxidants play a large role in the development and progression of Alzheimer's disease (AD) is not new. However, researchers have met with difficulties in efficiently monitoring the free-radical scavenging molecules in the brain. Yet now, new evidence from investigators at the National Brain Research Centre in Gurgaon, India, shows that the antioxidant,Read more
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Alzheimer's Progression Tracked through Antioxidant Levels
Oct 16,2018
Mouse Pups Have Two (Biological) Mommies
Using embryonic stem cells and gene editing, healthy mice have been bred from two mothers for the first time. The bimaternal mice not only lived into adulthood, they successfully reproduced with male mice to produce healthy offspring. Mice were also produced from two fathers, but, did not live past a few days.   The workRead more
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Oct 16,2018
Fat Tissue Found to Be a Surprising Source of Diabetes
A new study by Australian researchers is challenging what we know about the causes of diabetes. The new research points to fat tissue as a source of disease, and widens our understanding beyond the traditional focus on liver and pancreas as the main culprits.  The study ("Protein Kinase C Epsilon Deletion in Adipose Tissue, but NotRead more
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Fat Tissue Found to Be a Surprising Source of Diabetes
Oct 15,2018
Tracking Molecular Development of Sepsis May Lead to Improved Therapies
Sepsis remains a common and deadly condition that occurs when the body reacts to an infection in the bloodstream. Scientists know little about the early stages of the condition; however, physicians must act fast. Every hour that passes without one or more of the few treatments available increases the risk of death. Scientists at theRead more
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Tracking Molecular Development of Sepsis May Lead to Improved Therapies
Oct 15,2018
Novel Parkinson's Therapies Possible with New Mouse Model
Parkinson's disease (PD) is a neurodegenerative disorder that is marked by the accumulation of the protein, α-synuclein (αS), into clumps known as Lewy bodies, which diminish neural health. Now, researchers from Brigham and Women's Hospital (BWH) report the development of a mouse model to induce PD-like αS aggregation, leading to resting tremor and abnormal movement control.Read more
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Novel Parkinson's Therapies Possible with New Mouse Model
Oct 12,2018
Myopia Comes Into Gene Expression Focus
Myopia, or nearsightedness, develops through a molecular pathway distinct from the pathway that leads to hyperopia, or farsightedness. Resolving the molecular blur behind blurred vision, say scientists based at Columbia University, could sharpen the vision of drug developers interested in pharmacological treatments for myopia, which is not only the most common eye disorder, but aRead more
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Myopia Comes Into Gene Expression Focus
Oct 12,2018
Genes More Important Than Diet For Gout Risk
Despite accumulating evidence that gout isn't all about diet, the condition retains its reputation as the "rich man's disease” – or the disease that afflicts those who eat richly, regardless of their fortunes. Back in 2008, a study appeared suggesting that about 12% of gout cases could be attributed to dietary causes. A little later,Read more
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