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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Nov 01,2018
Early Liver Cancer Detection through Glycolytic Genes
The advantages of early detection in cancer screening cannot be overstated. Mountains of evidence exist showing the importance of intervening quickly not only to halt the spread of disease but also that survival rates improve dramatically for nearly all forms of cancer. Yet, identifying early markers of cancer remains a challenge for scientists. Although now,Read more
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Early Liver Cancer Detection through Glycolytic Genes
Nov 01,2018
Technical Guidelines for Drug Safety Pharmacology Research
The purpose of drug safety pharmacology research is to discover unexpected pharmacodynamic properties of the test substance that may be related to the clinical safety of humans, and to evaluate the adverse reactions and/or pathology of the test substance observed in toxicological tests and/or clinical studies The purpose of the QT interval study is mainlyRead more
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Technical Guidelines for Drug Safety Pharmacology Research
Oct 31,2018
Softening Up Chemo-Resistant Cancer Cells
DNA-damaging agents (DDAs) make up the most widely used group of cancer drugs. Yet their therapeutic success has been curtailed by drug resistance – either present in cancer cells from the disease onset or arising during treatment.   Now, scientists at the University of California San Diego (UCSD) have identified a gene that is involvedRead more
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Oct 31,2018
Growth Factor Significantly Impacts Fat and Carb Metabolism
A protein that has been under study for its role in cancer could represent a surprising new treatment for metabolic syndrome and associated disorders, such as type 2 diabetes and fatty liver disease. Studies in an obese mouse model by scientists at the Georgetown Lombardi Comprehensive Cancer Center showed that forcing expression of the naturalRead more
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Growth Factor Significantly Impacts Fat and Carb Metabolism
Oct 30,2018
Probiotics Are Not Always Good for You
Through research on gut inflammation, researchers have found that probiotics are not always 'good bacteria', and may not be good for everyone. Studies using a novel human "gut-inflammation-on-a-chip” suggest that probiotic bacteria may not always be a benefit to our health. Woojung Shin, Ph.D. student, and Hyun Jun Kim, Ph.D., assistant professor in the departmentRead more
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Oct 30,2018
Immunocompromised Patients Could Get Help from New Vaccine Strategy
Bolstering the immune system is not a new strategy when trying to protect against deadly pathogens, yet for those individuals that are immunocompromised, this therapeutic approach presents a particular challenge. For instance, while fungal pathogens rarely sicken healthy individuals, the incidence of fungal infections in people with HIV/AIDS or other immune deficiencies has risen sharplyRead more
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Immunocompromised Patients Could Get Help from New Vaccine Strategy
Oct 29,2018
Infant Microbiome Develops in Three Stages
By now, we know that the microbiome is important. But, despite all of the attention, exactly what role our commensal bacteria play in human disease remains largely unknown. Two papers were published back-to-back in Nature, the largest clinical microbiome studies done to date, that are trying to answer this question.   In one study, titled "TemporalRead more
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Oct 29,2018
Ear Infection Susceptibility Gene Identified
Those that have been affected by middle ear infections in their youth can attest to the anguish that this condition can have on daily life. Now, Researchers at the University of Colorado (CU) Anschutz Medical Campus have found multiple genetic variants within the FUT2 gene that makes some people especially susceptible to middle ear infections.Read more
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Ear Infection Susceptibility Gene Identified
Oct 26,2018
SIDS Link to Serotonin Neurons Strengthened
Sudden infant death syndrome or SIDS (also known as "cot death” or "crib death”) is the leading cause of death of young infants in the western world. Although the link between serotonin-producing neurons and their role in the regulation of breathing has been at the heart of SIDS research for many years, the cause ofRead more
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SIDS Link to Serotonin Neurons Strengthened
Oct 26,2018
Anti-Obesity "Biochemical Cigarette" Exploits Body's Responses to Cold and Smoking
Researchers in Europe and Australia have developed an anti-obesity "chemical cigarette" that exploits the body's natural responses to both cold exposure and smoking. The new approach uses two chemicals to boost energy expenditure and fat burning, while simultaneously dampening appetite, improving lipid metabolism, and reversing glucose intolerance. Tested in obese mice, the weight-loss approach couples.
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