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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Nov 08,2018
Anti-Inflammatory Bacterial Protein Discovered in Zebrafish
Scientists at the University of Oregon (UO) have identified a novel protein secreted by a common gut bacterium in zebrafish that reduces inflammation in the gut and delays death by septic shock. By examining how the protein, Aeromonas immune modulator (AimA), mutually benefits both the bacteria and their larval zebrafish hosts, the research team says itsRead more
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Anti-Inflammatory Bacterial Protein Discovered in Zebrafish
Nov 07,2018
Rare Genetic Disorder Research Opens Door to Novel Melanoma Therapy
Scientists who were studying a rare genetic disorder (NGLY1 deficiency) at the University of North Texas Health Science Center (UNTHSC) report the discovery of a novel targeted treatment for combating melanoma, a skin cancer that kills about 9,000 people in the U.S. States each year. Their study ("Stress and interferon signalling-mediated apoptosis contributes to pleiotropicRead more
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Rare Genetic Disorder Research Opens Door to Novel Melanoma Therapy
Nov 07,2018
"Leaky Gut" with Age Improved through Dietary Restriction
Flies eating a Spartan diet are protected from leaky gut and the systemic inflammation associated with it as they age. Conversely, flies on a rich Atkins-like diet are more prone to developing intestinal permeability, a condition linked to a variety of human conditions including inflammatory bowel disease.   Publishing in PLOS Genetics through an articleRead more
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"Leaky Gut" with Age Improved through Dietary Restriction
Nov 06,2018
Oily Fish Reduces Airway Inflammation in Asthmatic Children
Childhood asthma is the most common respiratory disorder worldwide, being associated with increased morbidity and a decreased quality of life.  Omega-3 fatty acids have anti-inflammatory and immunomodulating properties; however, their efficacy in asthma is controversial.   Regularly eating oily fish can help to reduce airway inflammation in children with asthma, according to the results ofRead more
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Nov 06,2018
Novel Two-Pronged Method Targets Cancer Cells' Telomerase and Chromosomes
An international team of researchers has developed a new technique for identifying potential cancer drugs that could streamline the development of therapies. The team devised a way to screen potential drug compounds to select those that interfere with tumor cells in two ways.   Their study ("Systematic Analysis of Compounds Specifically Targeting Telomeres and TelomeraseRead more
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Novel Two-Pronged Method Targets Cancer Cells' Telomerase and Chromosomes
Nov 05,2018
Research on Zika biomarker detection and prenatal diagnosis
Investigators at USC believe that after immunoprofiling a number of symptomatic Zika virus positive (ZIKV+) pregnant patients and extensive multiplexing analysis of their cytokine levels that they have identified a panel of biomarkers that are "specifically associated with symptomatic ZIKV+ infection during pregnancy.” This is an important discovery that could lead to screening tests andRead more
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Research on Zika biomarker detection and prenatal diagnosis
Nov 05,2018
No Appendix Equals Decreased Parkinson's Risk
In science, the mantra "correlation does not equate causation” is a cornerstone of proper data analysis and hypothesis formation. Yet, for researchers, this code is not a stopping point, but often a springboard to dive more deeply into the data and discover the mechanisms that led to the curious findings. When the data is supportedRead more
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No Appendix Equals Decreased Parkinson's Risk
Nov 02,2018
Fear in Mind: Coping Mechanism Identified in New Brain Region
A study conducted at Texas A&M University has identified a new area in the brain involved in inhibiting fear, a discovery that holds potential for clinical interventions in patients with psychiatric diseases such as post-traumatic stress disorder (PTSD).   Studies in rats by Stephen Maren, Ph.D., and colleagues have found that a small region ofRead more
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Nov 02,2018
Conjoined Cells Form a Potent Immunotherapy Combo
Shackled together, stem cells and platelets may help us escape cancer, report UCLA scientists. In the scientists' new study, the cancer is leukemia, and the defiant ones include a guide, a hematopoietic stem cell (HSC), and a drug carrier, an engineered platelet. The guide brings the duo into bone marrow, and the drug carrier deliversRead more
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Nov 01,2018
Vitamin D Connected to Cardio-Respiratory Fitness
Will drinking your milk daily provide you with the cardio fitness of a marathon runner? Probably not. However, new study data from investigators at the Virginia Commonwealth University (VCU) links vitamin D levels to cardiorespiratory fitness. While it is well established that vitamin D is important for healthy bones, there is a growing body ofRead more
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Vitamin D Connected to Cardio-Respiratory Fitness