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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jun 19,2020
Inclusion body protein purification and renaturation
Inclusion bodies: Under certain growth conditions, genetically engineered bacteria can accumulate certain special biological macromolecules, which are densely concentrated in cells, or enveloped by a membrane or form a bare membrane-free structure. This water-insoluble structure is called inclusion body. (Inclusion Bodies, IB). The composition and characteristics of inclusion bodies Generally contains more than 50% recombinantRead more
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Inclusion body protein purification and renaturation
Jun 19,2020
Medicilon Affinity Purification Technology Service
Medicilon affinity purification services mainly provide antibody affinity purification, tandem affinity purification, and antigen affinity purification. We have domestic excellent purification talents and advanced instruments and equipment to meet the needs of customers in purification. Affinity purification technology Affinity purification is the covalent European Union of one of the two molecules with affinity and solidRead more
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Medicilon Affinity Purification Technology Service
Jun 18,2020
Bio-Plex suspension chip multiple detection platform
The Bio-Plex suspension chip multiple detection platform can simultaneously detect up to 100 molecules in the same sample. Because of its good reproducibility in data, it is now widely used in immunology and various disease research. Such as cardiovascular disease, biomarker screening of tumor-specific markers, development of drug therapy targets, evaluation of drug treatment effects,Read more
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Bio-Plex suspension chip multiple detection platform
Jun 18,2020
The exploration path of liver disease NASH
Among people with obesity, diabetes, and metabolic syndrome, the global prevalence of non-alcoholic fatty liver disease (NAFLD) is as high as 25%, and the prevalence of ordinary adult non-alcoholic fatty liver disease (NASH) is 3% to 6%. It has become an increasingly important factor in cirrhosis, hepatocellular carcinoma and liver transplantation. NAFLD is currently aRead more
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The exploration path of liver disease NASH
Jun 18,2020
Bioavailability Research
Bioavailability: refers to the degree and speed of the release of active pharmaceutical ingredients from the preparation into the systemic circulation. Generally divided into absolute bioavailability and relative bioavailability. Absolute bioavailability is the relative amount of pharmacologically active ingredients absorbed into the body by intravenous preparations (usually considered as 100% bioavailability of intravenous preparations) asRead more
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Bioavailability Research
Jun 18,2020
Compound solubility test-Medicilon
Intrinsic solubility means that the drug does not contain any impurities, does not dissociate or associate in the solvent, and does not interact with the concentration of the saturated solution formed. It is one of the important physical parameters of the drug. Especially for new compounds. From the perspective of formulation, the characteristic solubility ofRead more
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Compound solubility test-Medicilon
Jun 18,2020
Biacore Technical Service: Biacore s200 and Biacore 8K
Biacore System BIA is the abbreviation of "Biomolecular Interaction Analysis” in English. BIAcore provides real-time observation of the interaction between biomolecules.
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Biacore Technical Service: Biacore s200 and Biacore 8K
Jun 18,2020
Toxicokinetics Test Service Company
"ADME” or "Toxicokinetics” is the process of studying the body's absorption, distribution, metabolism, and excretion of foreign chemicals. Medicilon Drug Safety Evaluation Service>> Toxicokinetic absorption, distribution, metabolism, excretion The toxicokinetics study used repeated doses of the toxicity test dose to study the dynamic changes of drugs in vivo, and obtained pharmacokinetic data. It is usuallyRead more
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Toxicokinetics Test Service Company
Jun 18,2020
R&D process of chemical pharmaceutical preparations
QTPP First, we need to determine the Quality Target Product Profile (QTPP), which includes clinical conditions of use, route of administration, dosage form and delivery system; dosage specifications; the release or delivery of the active ingredient of the drug, as well as affecting the pharmacokinetics of the drug The attributes of the product; the productRead more
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R&D process of chemical pharmaceutical preparations
Jun 18,2020
Stable cell line construction screening company
Shanghai Medicilon provides stable cell line services from animal models to cell function detection, has professional stable cell line builders, and can perform cell migration, invasion, apoptosis, cycle, and proliferation detection in the field of cell function detection , Cellular drug screening and other technical services. Stably expressing cell lines refers to the continuous andRead more
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Stable cell line construction screening company