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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jun 24,2020
Pharmacokinetic Research Services
Shanghai Medicilon has extensive experience in pharmacokinetics. Our pharmacy section provides customers with high-quality pharmacokinetic services from all small molecules to large molecules (proteins and antibodies), including in vitro ADME and in vivo pharmacokinetics and biological analysis. The animal species involved are non-human primates, dogs, mice, rats, rabbits, guinea pigs, etc. Among them, non-primate platformsRead more
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Pharmacokinetic Research Services
Jun 24,2020
Medicilon Metabolomics Technical Services
Metabonomics (metabonomics) refers to the analysis of group indicators, high-throughput detection and data processing, and the dynamic metabolic changes of the overall body or tissue cell system of graduate students, especially for endogenous metabolism, genetic variation, environmental changes and even various. The subject of the characteristics and effects of substances entering the metabolic system. MetabolomicsRead more
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Medicilon Metabolomics Technical Services
Jun 23,2020
Spotlight on PROTAC: Make "Undruggable" Targets Drugable
As researchers continue to explore new drug research and development, in recent years, there have emerged like protein motion (Protein Motion), targeted protein degradation complexes (PROTACs), gene transcription simulation (Transcriptional mimetic), small molecule co-receptor targeting ( SMART) and other emerging drug research and development technologies. As far as the overall development of drug research andRead more
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Spotlight on PROTAC: Make "Undruggable" Targets Drugable
Jun 23,2020
Ames Test
ICH recommended standard genotoxicity test combination Combination one a.Ames b. In vitro chromosome aberration test or in vitro micronucleus test or in vitro mouse lymphoma tk test, one of these three tests can be selected. c. In vivo micronucleus test or in vivo bone marrow cell chromosome aberration test; taking peripheral blood lymphocytes for cytogeneticRead more
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Ames Test
Jun 23,2020
Preclinical studies and clinical trials of drugs
1. Preclinical drug research (1) Pre-clinical research content 1. Literature research includes drug name and naming basis, the purpose and basis of the topic. 2. Pharmacy research. Raw material technology research, formulation prescription and technology research, confirmation of chemical structure or component test, drug quality test, drug standard drafting and description, sample inspection, auxiliary materials,Read more
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Preclinical studies and clinical trials of drugs
Jun 23,2020
Generic bioequivalence evaluation
Bioequivalence If the drug concentration is related to the therapeutic effect, it is assumed that the same subject takes different preparations and then measures the drug concentration in the blood at different time points. If the same blood drug concentration-time curve is obtained, it means that the same effect can be produced at the siteRead more
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Generic bioequivalence evaluation
Jun 23,2020
Cell Migration Experiment Service
Tumor cell migration is one of the most important features of malignant tumors. Tumor cells invade blood vessels or lymphatic vessels or body cavities from their primary site, and some cells are brought to another site or organ by blood and lymph fluid, where they multiply and grow to form The same type of tumorRead more
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Jun 23,2020
Gene Knockout Technology Service Company
The Medicilon gene knockout service has been successfully applied to model organisms such as cells, yeast, plants, zebrafish, mice, and rats. Gene knock-out is a technique for the targeted integration of foreign genes into a certain location on the genome of target cells through homologous recombination to achieve the purpose of targeted modification of aRead more
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Gene Knockout Technology Service Company
Jun 23,2020
Biomedical R&D Outsourcing Company
Pharmaceutical R&D Outsourcing Service Project Medicilon is known as one of the drug R&D outsourcing service companies (CRO). It has established a company in Shanghai that integrates compound synthesis, compound activity screening, structural biology, pharmacodynamic evaluation, pharmacokinetic evaluation and toxicology evaluation. The comprehensive technical service platform in line with international standards has been recognized byRead more
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Biomedical R&D Outsourcing Company
Jun 23,2020
Shanghai Drug Safety Evaluation Center
Medicilon has a professional team and practical experience in drug safety evaluation, which can provide high-quality data and a fast turnaround period to support various drug safety evaluation studies. Toxicological studies can be performed in accordance with non-GLP or GLP standards. Our research platform has been rated as Shanghai R&D Public Service Platform. Medicilon DrugRead more
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Shanghai Drug Safety Evaluation Center