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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Dec 04,2020
The Role of SiHa Cells in the Establishment of Mouse Cervical Cancer Animal Model
Cervical cancer is a disease that seriously threatens women's lives and health. The establishment of a mouse cervical cancer model can provide an experimental model for the research and development of new drugs and individualized treatments for cervical cancer. Human cervical squamous cell carcinoma SiHa cells are a kind of cells that can be usedRead more
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The Role of SiHa Cells in the Establishment of Mouse Cervical Cancer Animal Model
Dec 04,2020
Immunogenicity Testing Method of Biotech Drugs
Immunogenicity Testing Immunogenicity refers to the nature of drugs that stimulate the body to form specific antibodies or sensitized lymphocytes. In the development of biotechnology drugs, immunogenicity testing is an important task. For patients, immunogenicity will affect the safety and effectiveness of drugs, and even cause life-threatening dangers to patients because of the crossover ofRead more
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Immunogenicity Testing Method of Biotech Drugs
Dec 04,2020
SPR: Protein Kinase Activity Detection Method
Surface plasmon resonance As one of the most important potential drug targets at present, and a series of drugs targeting protein kinases have been successfully developed, various enzyme activity detection service companies are competing to develop related kinase detection methods and kits for screening and optimizing new ones Compounds are candidates for new drugs. SurfaceRead more
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SPR: Protein Kinase Activity Detection Method
Dec 04,2020
Factors Affecting the Immunogenicity of Biological Drugs
Many biopharmaceuticals are immunogenic in animals. Generally speaking, drugs that show strong immunogenicity to animals are also immunogenic to humans. Therefore, immunogenicity tests are required to evaluate the safety of drugs during the development of biological drugs. . For patients, immunogenicity easily affects the safety and effectiveness of drugs, and even causes new fatal diseasesRead more
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Factors Affecting the Immunogenicity of Biological Drugs
Dec 03,2020
The Advantages of CAR-T Therapy
Tumor immunotherapy has become an indispensable link in the clinical treatment of tumors. For example, the CAR-T cell therapy currently used in cancer treatment is a powerful immunotherapy, which transforms the patient's own immune T cells into chimeric expression Antigen receptors (CARs). A large number of tumor-specific CAR-T cells are generated by in vitro cultureRead more
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The Advantages of CAR-T Therapy
Dec 03,2020
What You Need to Konw in Western Blot Experiments
Western Blot, also known as western blot analysis and immunoblotting, is a technique widely used in the detection and analysis of proteins. It uses polyacrylamide gel electrophoresis. The detected substance is protein, and the "probe” is an antibody. "Use a labeled secondary antibody. Western blot analysis is an experimental method commonly used in molecular biology,Read more
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What You Need to Konw in Western Blot Experiments
Dec 03,2020
PET technology in CNS drug development
Central nervous system disease is a disease that seriously damages human physical and mental health. Its complexity, multi-factors, and multi-gene regulation and other characteristics have led to the unclear pathogenesis of related diseases. The development of CNS drugs is very important. Significance. The blood-brain barrier is a general term for the three barriers of "blood-brain”,Read more
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PET technology in CNS drug development
Dec 03,2020
Analysis of PET-CT Technology of Molecular Imaging
Partial imaging of the brain is of great significance for the study of brain function and the pathogenesis of neurological diseases and early diagnosis. The PET-CT technology, which combines the two imaging technologies of PET and CT, has the function of high sensitivity of positron emission imaging (PET)
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Analysis of PET-CT Technology of Molecular Imaging
Dec 03,2020
Understanding Reproductive Toxicity Studies: Types and Applications
What are 3 types of reproductive toxicity studies? (1)SegmentⅠ(fertility and early embryo development), (2) Segment Ⅱ (embryo-fetal development), (3) Segment Ⅲ (developmental toxicity test before and after birth).
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Understanding Reproductive Toxicity Studies: Types and Applications
Dec 03,2020
An Immunoassay Technique Based on Antigen-Antibody Reaction-RIA Immunoassay
Biopharmaceutical analysis can detect and study the quality of various biological drugs. Radioimmunoassay (RIA) is a method of biopharmaceutical analysis. This method is based on the basic principle that the radionuclide-labeled antigen competes with the unlabeled antigen in the reaction system to bind to specific antibodies to determine the amount of antigen in the sampleRead more
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An Immunoassay Technique Based on Antigen-Antibody Reaction-RIA Immunoassay