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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Dec 15,2020
Analysis of APC Gene, a Biomarker of Colon Cancer
The occurrence and development of cancer are related to the activation of multiple oncogenes and the inactivation of tumor suppressor genes. APC is a tumor suppressor gene that can be deleted or inactivated in 85% of colon cancers, whether in preclinical tumor models or in Clinical studies have found that the high expression and mutationRead more
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Analysis of APC Gene, a Biomarker of Colon Cancer
Dec 15,2020
Study on the Effect of High Expression of TRIML1 on Liver Cancer
It was first discovered that the TRIML1 coding substance is highly similar to the TRIM family protein in acute mice. It has been reported in the literature that the TRIM family plays an important role in many types of cancer, among which TRIML1, TRIM31, TRIM52 and TRIM59 can promote the occurrence and development of liver
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Study on the Effect of High Expression of TRIML1 on Liver Cancer
Dec 15,2020
Researchers Have Discovered a Molecule that Reduces Fat Mass in Mice-BAM15
Non-alcoholic steatohepatitis (NASH), also known as metabolic steatohepatitis, is a common chronic liver disease closely related to metabolic disorders such as obesity, insulin resistance, type II diabetes, and hyperlipidemia. NASH animal model is an important vehicle for studying non-alcoholic steatohepatitis. NASH is manifested by severe liver fat accumulation and inflammation, often accompanied by fibrosis andRead more
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Researchers Have Discovered a Molecule that Reduces Fat Mass in Mice-BAM15
Dec 14,2020
Medicilon mRNA Vaccine Bioanalysis Technology Platform
Medicilon mRNA Vaccine Bioanalysis Technology Platform Since 2020, the new crown disease has swept the world. With the raging epidemic, the development and large-scale application of the new crown vaccine has become the eager expectation of the world. Many domestic and foreign pharmaceutical companies have invested in the research and development samples of the newRead more
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Medicilon mRNA Vaccine Bioanalysis Technology Platform
Dec 09,2020
The Ideal Target Antigen for HPV Therapeutic Vaccine Development-E7
Human papillomavirus (HPV) is related to some tumors, such as cervical cancer, head and neck tumors, etc. E7 in HPV gene is the main transforming gene of the virus, and the sustained high-level expression of E7 protein is necessary for the maintenance of the malignant phenotype of tumor cells. E7 protein is a heterologous viralRead more
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The Ideal Target Antigen for HPV Therapeutic Vaccine Development-E7
Dec 09,2020
The Role of Dynamic Combinatorial Chemistry in the Discovery of Lead Compounds
In the new drug development process, wise selection of lead candidates can reduce the high proportion of drug elimination and the high cost of drug candidates that continue to increase in the development process. Discovery of lead compounds and optimization of lead compounds are critical to medical research and development. The combination of lead compoundRead more
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The Role of Dynamic Combinatorial Chemistry in the Discovery of Lead Compounds
Dec 08,2020
A New Way to Improve Sustained-release Drugs is Here
When taking sustained-release drugs, the drugs will slowly be released into the blood and provide help within a certain period of time. Tragedy can occur when the drug dissolves too slowly or too quickly. For example, OxyContin, which contains Oxycodone (the opioid family), normally provides 12 hours of pain relief, but in some patients itRead more
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Dec 08,2020
Miraculous and Powerful Anti-aging Drugs are Coming
Cognitive ability refers to the ability of the human brain to process, store and extract information. Although everyone wants to stay sharp forever, the impact of age on cognitive ability is a fact that cannot be ignored. Especially in the elderly, the decline in executive ability and the decline in learning and memory is veryRead more
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Dec 07,2020
Research on IL-33 in central nervous system diseases
Some neurological diseases are seriously plaguing people's lives and affecting people's health. The lack of suitable animal models that can truly reproduce the pathology and characteristics of human diseases also severely restricts the understanding of disease mechanisms. Central nervous system disease models are of great significance for studying the pathogenesis of central nervous system diseasesRead more
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Research on IL-33 in central nervous system diseases
Dec 07,2020
A chemical inflammatory agent that can induce colon cancer model
Dextran Sodium Sulfate (DSS) is a synthetic sulfate polysaccharide that can be used as an inflammatory agent to induce colon cancer models in mice. Oral administration of sodium dextran sulfate can directly damage colonic epithelial cells and induce inflammatory reactions by destroying the partition of commensal bacteria in the intestine.
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A chemical inflammatory agent that can induce colon cancer model
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