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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Dec 17,2020
Confirm the Structure of Drug to Find Whether the Structure of the Synthetic API is Correct
The preparation and research links of APIs are at a key position in the chemical drug R&D process, and only the same structure of the prepared compounds can ensure that subsequent quality control studies, pharmacological and toxicological studies and clinical studies are meaningful. Through the structure of the synthesized APIs Confirmation can characterize whether theRead more
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Dec 17,2020
Analysis on the Application of Enzyme Catalysis Technology in Green Chemistry
Green chemistry technology is an innovation to traditional chemistry. The green development of chemical synthetic drugs puts the protection of the environment first and avoids the discharge of harmful substances into the environment, which brings new challenges to traditional chemistry.
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Analysis on the Application of Enzyme Catalysis Technology in Green Chemistry
Dec 17,2020
Biocatalysis Technology to Improve Atomic Economy
Atomic economy and the 5 "R” principle are the core content of green chemistry technology. The 5 "R” principle refers to Reduction, Reuse, Recycling, Regeneration and Rejection. Atomic economy refers to the full use of each atom in the reactant, thereby It can make full use of resources and prevent pollution. The use of biocatalysisRead more
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Biocatalysis Technology to Improve Atomic Economy
Dec 17,2020
Analysis of the Role of Plasma Stability Determination in Drug Development
There are a variety of hydrolytic enzymes in plasma. If the compound to be studied has affinity for one of these enzymes and has a hydrolyzable group at a suitable position, then the compound can be decomposed in plasma. Thereby affecting the accuracy of biological test conclusions or making it unable to reach an effectiveRead more
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Analysis of the Role of Plasma Stability Determination in Drug Development
Dec 17,2020
Three Characteristics of the Production of Pharmaceutical Intermediates
The various products between the production of raw materials are pharmaceutical intermediates, and the synthesis of pharmaceuticals has a strong dependence on the intermediates. Pharmaceutical intermediates are important raw materials for the production of APIs and belong to the category of chemical products. The production plant does not require GMP certification. And its production hasRead more
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Three Characteristics of the Production of Pharmaceutical Intermediates
Dec 17,2020
The Role of QbD Concept in Designing and Optimizing Prescription Technology
The International Coordinating Committee for the Registration of Technical Standards for Human Drugs (ICH) put forward the QbD concept (quality comes from the design concept) in the ICH Q8(R2) issued in 2009, and its main goal is consistent drug product quality or performance and subsequent cost reduce. The application of QbD concept in formulation designRead more
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Dec 16,2020
Several Major Issues that Need to be Paid Attention to API Process Scale-up
The quality of the active ingredient of the drug, the bulk drug, largely affects the safety and effectiveness of the drug. In order to ensure the production quality of medicines and the safe use of medicines for the people, it is necessary to pay attention to the GMP on-site management of the raw material medicineRead more
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Several Major Issues that Need to be Paid Attention to API Process Scale-up
Dec 16,2020
How to Screen the Cost-effective Route of API and Intermediates
The active ingredient in the preparation, API, is intended to be used in any substance or mixture of substances in the manufacture of pharmaceuticals. Pharmaceutical intermediates are important raw materials for the production of APIs. The production of drugs can rely on the custom synthesis of intermediates. After the synthesis of APIs, mid-scale and industrializedRead more
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How to Screen the Cost-effective Route of API and Intermediates
Dec 15,2020
Preclinical Research and Clinical Trials of Drugs
1. Drug Preclinical Research (1) Preclinical research content 1. Literature research, including the name of the drug and the basis for naming, and the basis for establishing the title. 2. Pharmaceutical research: API process research, preparation formulation and process research, test to confirm chemical structure or composition, drug quality test, drug standard drafting and description,Read more
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Preclinical Research and Clinical Trials of Drugs
Dec 15,2020
Green Chemistry Technology: Photoredox Reaction
The occurrence of chemical reactions depends on the generation of free radical intermediates. Free radical intermediates are atoms or groups with unpaired electrons formed by the homogenization of covalent bonds. The breaking of covalent bonds in traditional chemical reactions often requires extreme conditions such as high temperature and pressure, or substances with harmful radioactivity toRead more
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Green Chemistry Technology: Photoredox Reaction
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