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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jan 29,2021
Consistency Evaluation of Generic Drugs, Bulk Drug Particle Size Control Needs Attention
In the development of formulation, due to the different synthesis processes of raw materials from different sources, there may be differences in their solubility, crystal form, particle size, and impurities, which may affect the consistency of the product. In the evaluation of the consistency of generic drugs, the particle size control of raw materials shouldRead more
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Consistency Evaluation of Generic Drugs, Bulk Drug Particle Size Control Needs Attention
Jan 28,2021
Three Ways to Improve the Bioavailability of Poorly Soluble Drugs
Due to the difference in particle size or added excipients of poorly soluble drugs, the oral dose will be the same, but the efficacy will be very different. In the development of solid preparations, increasing the solubility of poorly soluble drugs and improving the bioavailability of drugs, thereby promoting the absorption of drugs in theRead more
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Three Ways to Improve the Bioavailability of Poorly Soluble Drugs
Jan 28,2021
Nature: There is no Paralyzed Patient, and the Days of Freedom are not Far Away
The team created a “designer” signaling protein and injected it into the brains of animals to stimulate their nerves. The cells regenerate and share the recipe for making the protein. The research was published in Nature recently. Nature: There is no paralyzed patient, and the days of freedom are not far away Spinal cord injuryRead more
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Jan 28,2021
COVID-19: The Virus Keeps Mutating, is Our Vaccine Still Effective?
Recent viral mutations of COVID-19 may inhibit the effectiveness of the current two vaccines to a certain extent. Researchers have recently expressed concern about this preliminary finding, because it also largely predicts that future mutations may destroy the vaccine's effectiveness. Effectiveness. The study tested coronaviruses from the United Kingdom, South Africa, and Brazil, and wasRead more
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COVID-19: The Virus Keeps Mutating, is Our Vaccine Still Effective?
Jan 27,2021
Analysis on the Benefits of Innovative Drug Release Technology in Drug Development
Compared with the research and development of new entity drugs, the research and development of innovative drug preparations has the advantages of low cost, short cycle and quick effect. Preparation technology innovation, drug delivery route innovation, drug dosage form innovation, drug delivery plan innovation, and packaging innovation are all important technologies for the development ofRead more
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Jan 27,2021
Factors Affecting the Stability of Antibody Drugs: Glycosylation Modification
As an important biotechnology drug, the emergence of monoclonal antibody drugs provides a brand new approach for the treatment of various diseases such as cancer, autoimmune diseases and viral infections. Glycosylation modification is an important factor affecting the biological characteristics of monoclonal antibody drug structure, function development and pharmacokinetics. The most obvious effect of proteinRead more
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Factors Affecting the Stability of Antibody Drugs: Glycosylation Modification
Jan 27,2021
Analysis on the Preparation and Development Trend of Monoclonal Antibodies
Currently, monoclonal antibody cloning drugs, protein drugs, gene and nucleic acid drugs, etc. are the focus of my country's biopharmaceutical research and development. Among them, monoclonal antibody drugs, as a biologically targeted drug with unique advantages, have high specificity, strong targeting and the characteristic of low toxicity and side effects is remarkable in treating diseases.Read more
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Analysis on the Preparation and Development Trend of Monoclonal Antibodies
Jan 27,2021
Analysis on the Composition and Preparation Process of Oral Solid Preparations
Oral solid preparations are the preferred dosage form in clinical use, including oral powders, granules, tablets, capsules and dripping pills. They have good physical and chemical stability, low production and manufacturing costs, and are more convenient to take and carry. Features. In the research and development of solid preparations, the formulation of dosage formsRead more
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Analysis on the Composition and Preparation Process of Oral Solid Preparations
Jan 26,2021
Analysis on the Role of Dissolution Test in Evaluating the Quality of Medicine
The consistency evaluation of the quality and efficacy of the generic drug requires that the generic drug and the reference preparation have the same quality attributes and clinical efficacy. In the consistency evaluation of the generic drug, effective methods are adopted to accurately evaluate the drug’s in vivo and in vitro correlation (IVIVC) Is anRead more
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Jan 26,2021
How Much do You Know about the BE Test?
Bioequivalence test, also known as BE test, refers to the use of bioavailability research methods, using pharmacokinetic parameters as indicators to compare the same or different formulations of the same drug under the same test conditions. The human body test whether there is statistical difference in the absorption degree and speed of the active ingredient.
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How Much do You Know about the BE Test?
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