Contact Us

marketing@medicilon.com

ABOUT

Company Profile

Corporate Culture

Management Team

Company History

Message from the CEO

Honors and Awards

SERVICES

SERVICES

01 Drug Discovery

Chemistry Research Biology Research Early Pharmacokinetics

02 Pharmaceutical Research

Intermediates Active Pharmaceutical Ingredients Pharmaceutical preparation Analytical Method Development and Quality Control CMC Filings Analytical Testing Center

03 Preclinical Research

Pharmacology & Pharmacodynamics Drug Safety Evaluation DMPK Bioanalysis IND Filings

PLATFORM

PLATFORM

01 One-stop Integrated Services

Liposome Drug Development Drug Discovery Pharmaceutical Research Preclinical Research Botanical Drug Preclinical R&D

02 Innovative Drug R&D Services

Peptide Drug Conjugate (PDC) Antibody Nucleic Acid Drug Cellular Immunotherapies mRNA Vaccine PROTAC ADC

03 Key Technical Services for Drug R&D

Cytokine and Biomarker Detection Metabolite Identification (MetID) Drug Forming Research Flow Cytometry Technology SEND Format Conversion Flow Sorting NanoString nCounter Detection Routes of Drug Administration

04 Drug Efficacy Evaluation for Common Diseases

Rodent Cerebrovascular Disease Inflammatory and Immune Diseases IO Pharmacodynamic Model

05 High-end Preparations Technology Platform

Skin Topical Preparation Ophthalmic drug Inhalation drug

06 Targeted Drugs R&D Services

STAT3-targeted Drugs R&D Service KRAS-targeted Drugs R&D Service GLP-1 New Drug R&D Service

07 Safety Assessment Lab of Process Chemistry

08 Public Services

CAREERS

Talent Development

Campus Recruitment

Recruitment

NEWS

Medicilon Events

Featured Stories

Market Events

Videos

A.C.E.

INVESTORS

Stock Information

Investment Contact

CLIENT CENTER

Intellectual Property Protection

Clients Testimonials

Downloads

Partnerships

Medicilon Support

Newsletters

CN

中

News and Events

Medicilon Events Featured Stories Market Events Videos A.C.E.

HomenewsFeatured Stories

Featured Stories

Hot information：

Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021

Introduction to indirect immunofluorescence

What is immunofluorescence technology? Immunofluorescence technology is an immunoassay technique that combines the specificity of antigen-antibody reaction with the sensitivity and intuitiveness of fluorescent substance detection. What are the types of immunofluorescence technology? Fluorescent antibody staining technology: fluorescence microscopy technology, flow cytometry immunofluorescence technology (2) Fluorescence immunoassay: time-resolved immunoassay, fluorescence polarization immunoassay What are theRead more

Introduction to indirect immunofluorescence

Direct Fluorescent Antibody Test

Fluorescent Antibody Test is based on the principle of antigen-antibody reaction. Firstly, the known antigen or antibody is labeled with fluorescein to make fluorescent antibody, and then this fluorescent antibody (or antigen) is used as a probe to detect the corresponding antigen in the tissue or cell (Or antibody). The antigen-antibody complex formed in theRead more

Direct Fluorescent Antibody Test

Indirect immunofluorescence method for antibody detection

What is indirect immunofluorescence method for antibody detection? 1. Basic principles: The staining procedure is divided into two steps. In the first step, an unknown unlabeled antibody (specimen to be tested) is added to the known antigen sample, and the sample is incubated at 37°C for 30 min in a humidified box to fully bindRead more

Indirect immunofluorescence method for antibody detection

Immunofluorescence sample labeling detected by flow cytometry

Introduction: Commonly used fluoresceins for flow cytometry detection include FITC, TRITC, Cy3, Cy5, PE and PI. Among the above various fluorescent dyes, PE has the strongest fluorescence and is suitable for weakly expressing antigens; FITC is the cheapest and is suitable for strong Express antigen, wide application range. 1 Flow cytometer (Flow cytometer) is aRead more

Immunofluorescence sample labeling detected by flow cytometry

Indirect immunofluorescence detection of autoantibodies

The standard technique for autoantibody diagnosis is indirect immunofluorescence, which is characterized by strong specificity and obvious signal intensity contrast between positive and negative samples. Microscopic observation can accurately determine the distribution of fluorescence in tissues or cells. The position of the autoantigen determines the typical fluorescence pattern of its corresponding antibody, and the stainingRead more

Indirect immunofluorescence detection of autoantibodies

The latest progress and development trend of autoantibody indirect immunofluorescence detection technology

Autoantibody detection is an important method for diagnosing autoimmune disease (autoimmune disease, AID). Commonly used detection methods include indirect immunofluorescence (IIF), enzyme-linked immunoassay (ELISA), western blotting, etc., with the continuous innovation of biotechnology , Auto-antibody detection has been gradually applied to autoantibody detection by technologies such as magnetic bead particle chemiluminescence, immune microarray, and flowRead more

The latest progress and development trend of autoantibody indirect immunofluorescence detection technology

Precautions for the selection of immunofluorescence double-labeled antibodies

Double immunofluorescence When detecting two antigens at the same time in the same tissue or cell sample, double fluorescent staining is required. Double immunofluorescence labeling method (double immunofluorescence labeling method) is also divided into direct method and indirect method. Direct double immunofluorescence labeling Direct double immunofluorescence labeling: mix two different fluorescein-labeled antibodies (such as anti-ARead more

Precautions for the selection of immunofluorescence double-labeled antibodies

Fluorescein FITC-labeled antibody method

Immunofluorescence technology combines fluorescein such as fluorescein isothiocyanate (FITC) with the corresponding antibody (or antigen) in a chemical way, and combines the fluorescent-labeled antibody (or antigen) with the corresponding antigen in the specimen to form a fluorescent-labeled antibody -Antigen complex, observe with a fluorescence microscope. The presence of fluorescence under the microscope indicates the presenceRead more

Fluorescein FITC-labeled antibody method

Application of fluorescent antibody in clinical diagnosis and treatment

Autoimmune disease refers to a series of pathological immune responses produced by the body's immune effect or immune effector molecules against one's own tissues or cells, leading to a large class of diseases that damage their own tissues and organs. The pathogenesis is very complex and the clinical manifestations are variable. , Often involving theRead more

Application of fluorescent antibody in clinical diagnosis and treatment

Fluorescent Antibody Technique

Fluorescence immunoassay technology is one of the earliest developed labeling immunoassay techniques. For a long time, some scholars have tried to combine antibody molecules with some tracer substances, and use antigen-antibody reaction to locate antigenic substances in tissues or cells. Coons was equal to the first successful use of fluorescein for labeling in 1941. ThisRead more

Fluorescent Antibody Technique

Global

Address: 20 Maguire Road, Suite 103, Lexington, MA 02421(America)

Tel: +1(781)535-1428(U.S.)

Address: Allia Future Business Centre Kings Hedges Road Cambridge CB4 2HY, UK

Tel: 0044 7790 816 954 (Europe)

Email: marketing@medicilon.com

Address: 5th Floor, 62, Banpodae-ro 4-gil, Seocho-gu, Seoul, 06719 South Korea

Tel: +82 70-8269-5849

China

Address: No.585 Chuanda Road, Pudong New Area, Shanghai (Headquarters)

Postcode: 201299

Tel: +86 (21) 5859-1500 (main line)

Fax: +86 (21) 5859-6369

© 2023 Shanghai Medicilon Inc. All rights reserved All Rights Reserved Privacy Policy

-->