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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Mar 16,2021
PDC platform Cybrexa Therapeutics completes US$25 million in Series B financing
On March 10, 2021, Cybrexa Therapeutics, Inc., a biotech company focused on oncology, announced the completion of a $25 million Series B funding round to develop novel therapies through its Alphalex ™ Peptide Drug Conjutate (PDC) oncology targeting platform.The financing includes Highcape Capital and new investor Elm Street Ventures.The funds raised will be used toRead more
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PDC platform Cybrexa Therapeutics completes US$25 million in Series B financing
Mar 15,2021
Study on the stability of in vitro diagnostic reagents-summary of key points
Stability research is an important content that runs through the entire reagent research and development stage and supports the marketing and post-marketing research of reagents, and is the basis for setting the validity period of the product. Since stability is the ability of a product to maintain stable components, properties and performance, in the processRead more
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Study on the stability of in vitro diagnostic reagents-summary of key points
Mar 15,2021
Relevant explanations on the experimental design of stability studies
The experimental design of stability study should be carried out according to different research purposes, combined with the physical and chemical properties of the drug substance, the characteristics of the dosage form, and the specific prescription and process conditions. Next, we will explain the specific sections by section. The batch and scale of the sampleRead more
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Relevant explanations on the experimental design of stability studies
Mar 12,2021
Preclinical and clinical research of new drugs
In 10 years, it has spent 1 billion US dollars to develop a new drug. Whether it is driven by profit or the sense of accomplishment in saving thousands of patients, this behavior of pharmaceutical companies deserves our respect. What process does a new drug go through from research and development to market launch? WhatRead more
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Preclinical and clinical research of new drugs
Mar 12,2021
What is Preclinical in Vitro and in Vivo Research
Before testing candidate drugs in humans, their safety and efficacy (effectiveness) must be explored in preclinical studies. These studies can be "in vitro”, which means "in a container” in Latin, which refers to research using cell culture in vitro, or "in vivo”, which means "in vivo” in Latin. Refers to the research conducted inside theRead more
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What is Preclinical in Vitro and in Vivo Research
Mar 11,2021
Inhaled vaccines can induce rapid and strong immune responses in mice and non-human primates
In a proof-of-concept study, the researchers demonstrated that the phage-based inhalation delivery system used for vaccines can generate effective antibody responses in mice and non-human primates without causing lung damage. The results of the study indicate that a safe and effective pulmonary delivery system could one day be used for vaccines and therapeutics against respiratoryRead more
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Inhaled vaccines can induce rapid and strong immune responses in mice and non-human primates
Mar 11,2021
Summary of non-human primate models of autism
In the past few decades, rodents have been widely used to study the pathogenesis of ASD. However, there are major evolutionary differences between rodents and humans in social behavior and brain anatomy. To this end, in addition to rodent models of autism (summary from the previous issue: [Collection] three thousand words to summarize commonly usedRead more
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Mar 11,2021
Models of aging in non-human primates
The human population has begun to continue to transform into an elderly population, which requires biomedical research to better understand the basic biology of aging and age-related diseases, and to promote new and improved treatment options. The breadth of carrying out this research is impractical, so animal models are needed to decompose the complexity ofRead more
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Models of aging in non-human primates
Mar 10,2021
Pharmacokinetics and biological analysis of ophthalmic drugs
Eyes are the most sensitive organs of human beings. Generally, their sophisticated functional structure prevents foreign bodies from intruding or removing foreign bodies. The importance of eyes is self-evident, but eye diseases are too numerous to mention. There are currently more than 500 eye diseases known, such as refractive errors (myopia, hyperopia, astigmatism), dry eye,Read more
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Pharmacokinetics and biological analysis of ophthalmic drugs
Mar 10,2021
Pharmacokinetics and Bioanalysis of Chiral Drugs
Stereoisomers are compounds in which the structural groups in the molecule are arranged differently in three dimensions without changing the atomic composition, atom-atom connection mode, and bonding sequence. Stereoisomers are divided into two categories: Enantiomers and Diastereoisomers. Enantiomers (ie, enantiomers) refer to stereoisomers that cannot overlap in space and are mirror images of each other,Read more
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Pharmacokinetics and Bioanalysis of Chiral Drugs
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