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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Mar 19,2021
Detailed Explanation of Pre-prescription Research-Formulation
Pre-formulation research has gradually become a routine research project in the design and improvement of dosage forms and preparations, providing a basis for further designing dosage forms and optimizing the formulation process of preparations. The main content of pre-formulation research work is to obtain various information required for dosage form and preparation design by consultingRead more
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Detailed Explanation of Pre-prescription Research-Formulation
Mar 19,2021
Analytical chemistry experiment specifications and precautions Experimental water
Analytical chemistry experiments should use pure water, generally distilled water or deionized water. Some experiments require the use of double distilled water or higher specifications of pure water (for example, experiments in electroanalytical chemistry, liquid chromatography, etc.). Pure water is not absolutely free of impurities, but the content of impurities is very small. Note: ItRead more
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Mar 18,2021
The Development Trend of Modern Analytical Chemistry
Factors affecting the stability of traditional Chinese medicine preparations Chemical degradation reactions of drugs: hydrolysis, oxidation, isomerization, polymerization, decarboxylation, etc. Main degradation pathways: hydrolysis and oxidation. Types of drugs that are easily hydrolyzed and easily oxidized (1) Types of easily hydrolyzed drugs ① Ester drugs: Andrographolide; ②Amide drugs: penicillin; ③Glycoside drugs: Cardiac glycosides are easilyRead more
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Mar 18,2021
Factors affecting the stability of traditional Chinese medicine
Factors affecting the stability of traditional Chinese medicine preparations     Chemical degradation reactions of drugs: hydrolysis, oxidation, isomerization, polymerization, decarboxylation, etc. Main degradation pathways: hydrolysis and oxidation. 1. Types of drugs that are easily hydrolyzed and easily oxidized (1) Types of easily hydrolyzed drugs ① Ester drugs: Andrographolide; ②Amide drugs: penicillin; ③Glycoside drugs: Cardiac glycosidesRead more
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Factors affecting the stability of traditional Chinese medicine
Mar 18,2021
Analysis on the factors affecting the stability of preparations
Factors affecting the stability of pharmaceutical preparations can generally be divided into prescription factors and non-prescription factors. Prescription factors include raw materials and excipients; non-prescription factors include temperature, light, humidity, oxygen, packaging, etc.
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Analysis on the factors affecting the stability of preparations
Mar 18,2021
The stability of the formulation
Stability research is the feedback of the quality of the preparation product, and it is the verification of the applicability of the product formulation process and packaging materials. It is the most important part of the entire pharmaceutical research. It will be the most indispensable part of the entire drug development cycle. Stability test researchRead more
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The stability of the formulation
Mar 17,2021
Why the dissolution of the formulation in the stability test becomes slower?
The stability study of preparations is to investigate the law of the quality characteristics of preparations over time under the influence of various environmental factors (such as temperature, humidity, light exposure, etc.), and based on this, it is the prescription, process, packaging, and storage conditions of the drug. Provide supporting information for the determination ofRead more
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Why the dissolution of the formulation in the stability test becomes slower?
Mar 17,2021
Summary of the content of the stability test of the CTD data of the raw materials and preparations
The purpose of stability test is to investigate the law of raw material drug changes over time under the influence of temperature, humidity, and light, to provide scientific basis for the production, packaging, storage, and transportation conditions of the drug, and to establish the validity period of the drug through the test. The basic requirementsRead more
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Mar 16,2021
Stability Studies of Bulk Drugs or Preparations
Stability research runs through the entire stage of drug research and development. This article mainly outlines the general principles and precautions in the drug stability research process from the perspectives of new/generic APIs and the stability of new/generic formulations. effect. The origin of the storage conditions of the stability test According to the concept proposedRead more
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Stability Studies of Bulk Drugs or Preparations
Mar 16,2021
Relevant explanations on the stability research of pharmaceutical preparations
The stability study of the formulation should be designed based on the understanding of the characteristics of the drug substance and the test results obtained from the stability study of the drug substance and the clinical prescription study, and the possible changes during the storage process and the investigation of the stability test should beRead more
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Relevant explanations on the stability research of pharmaceutical preparations