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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Oct 29,2015
Functions In Histones To Reveal Damaged DNA Repair
    Scientists at the University of Copenhagen say they have located a previously unknown function for histones, which help in further studies for understanding how cells protect and repair DNA damages. This new discovery may be of great importance to the treatment of diseases caused by cellular changes such as cancer and immune deficiency syndrome.     “IRead more
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Oct 29,2015
Insulin Surges Lap against Pleasure Center of Brain
    The rise and fall of insulin levels is connected to the rise and fall of dopamine levels in the brain, though the net effects in certain brain regions have been hard to determine. In the hypothalamus, insulin activates insulin receptors, favoring dopamine reuptake and signaling satiety after a meal. In the striatal region, however, insulin'sRead more
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Insulin Surges Lap against Pleasure Center of Brain
Oct 28,2015
Protein Acts as Sensor to Guard against Obesity and Diabetes
    Scientists in Australia have identified an internal sensor that helps fight obesity by instructing cells to burn their fat stores. The finding could play a major role in the fight against obesity and metabolic diseases, including type 2 diabetes.     In the study ("IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome”), published inRead more
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Oct 28,2015
Modeling Genetic Diseases in Mini Kidney Organoids
    Kidney-like tissues and even kidney organoids—mini-kidneys—have already been created by means of stem cell choreography, but now some new steps are being introduced. With the addition of genome editing, kidney organoids are showing more promise than ever as disease modeling and drug development platforms.  Human-pluripotent-stem-cell-derived kidney cells (hPSC-KCs) have important potential for disease modelling andRead more
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Oct 27,2015
The Top CRO Companies of 2015
Nice Insight's Top Companies lists are comprised of the highest scoring companies, as rated by buyers of outsourced services, with respect to customer perception within each category. Customer perception describes how a current buyer or prospect rates a company based on the information they have been exposed to—from marketing materials to word-of-mouth influence, as wellRead more
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The Top CRO Companies of 2015
Oct 27,2015
Big Data Screen Uncovers New Cancer Driver Genes
Using publicly available information from genomic and proteomic databases, a team of scientists lead by researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have created a new and more comprehensive catalog of driver mutations for cancer. Driver mutations are genes that handle the progression of cancerous growths. The researchers used cancer mutation and proteinRead more
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Big Data Screen Uncovers New Cancer Driver Genes
Oct 27,2015
Algae Virus can infiltrate Mammalian Cells could Cause Cognitive Decline
    New research led by the University of Nebraska-Lincoln has provided the first direct evidence that an algae-infecting virus can invade and potentially replicate within some mammalian cells.  Known as Acanthocystis turfacea chlorella virus 1, or ATCV-1, the pathogen is among a class of chloroviruses long believed to take up residence only in green algae. ThatRead more
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Oct 26,2015
Largest Ever Genomic Study for Eczema Finds New Genetic Risk Factors
    With cold winter temperatures looming around the corner for much of the northern hemisphere, the arid frigid air seemingly brings along with it dry, itchy skin. Yet, for a fair number of people, this type of skin malady is a constant part of life, regardless of the season.     Atopic dermatitis—commonly known as eczema—is an inflammatoryRead more
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Oct 26,2015
Researchers Hope to Treat Alzheimer by Increasing Brain Function
    Increasing a protein that binds cholesterol to membranes in nerve cells in the brain can improve learning and memory in elderly mice, which might lead to treatments for Alzheimer's and similar disease in humans, scientists at The Scripps Research Institute, the Veterans Affairs San Diego Healthcare System (VA), and University of California (UC) San DiegoRead more
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Oct 23,2015
DNA “Backpack Buckle” Works to Regulate Gene Expression
    Genomic loop formation is a well-documented method that the cellular machinery uses to regulate the expression of various genes within human chromosomes. Yet, how these loops form and fold has eluded scientists for a number of years.     Now, researchers based at Houston’s Texas Medical Center have found that a protein complex that forms the geneRead more
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