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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Nov 25,2015
Novel Nanocarriers Open Door to Better Treatment for Brain Cancer
A Lawrence Berkeley National Laboratory researcher thinks she might have found a solution to transporting therapeutics across the blood-brain barrier to treat a deadly form of brain cancer. Ting Xu, Ph.D., a polymer scientist specializing in self-assembling bio/nano hybrid materials, has developed a new family of nanocarriers formed from the self-assembly of amphiphilic peptides and polymers.
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Novel Nanocarriers Open Door to Better Treatment for Brain Cancer
Nov 23,2015
New Antibiotic Resistance Gene That Breaches 'Last Line of Defense'
    A new gene has been discovered that allows bacteria to become resistant to our last line of antibiotic defense. The gene, MCR-1, was found to be widespread in pigs and patients in south China, with some strains having epidemic potential.  MCR-1 was found to enable bacteria to become resistant to polymyxins; the colistin and polymyxinRead more
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Nov 23,2015
Single Gene Found to Play Huge Role in Brain Development
    Researchers at the Institute of Molecular Biology (IMB) in Mainz, Germany say they have unraveled a complex regulatory mechanism that explains how a single gene can drive the formation of brain cells. Their study ("NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program”), published in The EMBO Journal, is an important stepRead more
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Single Gene Found to Play Huge Role in Brain Development
Nov 23,2015
RNA-Based Drugs Give More Control Over Gene Editing
In just the past few years, researchers have found a way to use a naturally occurring bacterial system known as CRISPR/Cas9 to inactivate or correct specific genes in any organism. CRISPR/Cas9 gene editing activity runs continuously, though, leading to risk of additional editing at unwanted sites. Now, researchers at University of California, San Diego SchoolRead more
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Nov 23,2015
Nano Sensor Measures MicroRNAs Could Speed Up Cancer Detection
    The role of microRNAs in the detection of various types of cancer has become increasingly evident over the past several years. However, a major drawback of using these molecules as a diagnostic indicator of disease has been developing a method that is sensitive enough to detect minuscule amounts of the genetic material in a timeframeRead more
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Nano Sensor Measures MicroRNAs Could Speed Up Cancer Detection
Nov 20,2015
Novel Therapeutics Show Promise for Treating Persistent Tuberculosis
    Researchers from the Florida campus of the Scripps Research Institute (TSRI) say they have discovered several first-in-class compounds that target inactive Mycobacterium tuberculosis bacteria that hide inside cell aggregates, latent and persistent, waiting to break out. The researchers described a technique in ACS Chemical Biology ("First-in-Class Inhibitors of Sulfur Metabolism with Bactericidal Activity against Non-ReplicatingRead more
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Nov 20,2015
Researchers Discover Novel Cancer Immunotherapy Target
    Scientists from the Institut de recherches cliniques de Montreal (IRCM) led by André Veillette, M.D., have identified the mechanism of action for a new target for novel immune-oncology treatments. Their discovery ("DNAM-1 controls NK cell activation via an ITT-like motif”) is described in the Journal of Experimental Medicine.     The researchers study natural killer (NK) cells,Read more
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Researchers Discover Novel Cancer Immunotherapy Target
Nov 20,2015
Small Molecule Drug Candidates
Modern drug development is no longer a "Shen Nong tastes herbs” model. First, it is ethically not allowed. Drugs that enter the clinic must not only have a certain basis for patient benefit, but also ensure safety. Second, if certain screening is not carried out, there are too many compounds to be tested clinically, whichRead more
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Small Molecule Drug Candidates
Nov 19,2015
Human Brain Peeled Back to Its Transcriptional Core
The human brain has so many organizational layers that you might wonder whether there is, deep down, a core that we all share, however diverse our brains are in other respects. It turns out that there is a core, report scientists at the Allen Institute for Brain Science. This core, the scientists say, is transcriptionalRead more
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Nov 19,2015
Scientists Turn Bacterial Molecules into Potential Drug Molecules
    Scientists have figured out how to turn bacterial molecules into potential drug molecules.   Scientists at Syracuse University say they have created molecules that mimic and dominate toxic ones secreted by bacteria. They believe that these molecules might be turned into potential drugs.     “Using toxic molecules to develop therapeutic agents, such as a vaccine, is notRead more
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