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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Dec 08,2015
Guided Ultrasound Plus Nanoparticle Chemotherapy Cures Tumors
    Thermal ablation with magnetic resonance–guided focused ultrasound surgery (MRgFUS) is a noninvasive technique for treating fibroids and cancer. MRgFUS combines an ultrasound beam that heats and destroys tissue with magnetic resonance imaging to guide the beam and monitor the effects of treatment.  New research from UC Davis shows that combining the technique with chemotherapy can allowRead more
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Dec 08,2015
Genetic Link between Heart and Neurodevelopmental Disease
    Children with significant congenital heart disease have a far better chance of surviving today than in decades past, thanks to major advances in surgery. But some infants who recover from repairs to their hearts later show the effects of delays in brain development, including impairments to cognitive, language and social functioning. Such impairments can affectRead more
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Dec 07,2015
Bacteria-Killing Bacteria Study May Open Door to Fighting Microbial Resistance
    Scientists from the Universities of Nottingham and Birmingham report that they have discovered how a potentially useful predatory bacterium called Bdellovibrio protects itself against its own weapons when it invades other bacteria. The researchers say their work offers insights into early steps in the evolution of bacterial predators and will help to inform new waysRead more
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Dec 07,2015
Mitochondria Affect Stress Responses
    Mitochondria, the tiny structures inside our cells that generate energy, may also play a previously unrecognized role in mind-body interactions. Based on new studies of stress responses, this insight may have broad implications for human psychology and for the biology of psychiatric and neurological diseases.     These possibilities were raised by a study that aligned mutationsRead more
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Dec 04,2015
Measuring Cell Squishiness Could Aid Cancer Drug Discovery
    In this modern genomic age, it would almost seem archaic to devise a screening method that relies on changes in cellular architecture that occur when a cell turns cancerous and not on molecular mutations. However, sometimes the simplest and most direct solutions provide the best results.     Since scientists previously established that many types of cancerRead more
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Dec 04,2015
Scientists Create Fingerprints for Major Drug Development Targets
    For the first time, scientists from the Florida campus of The Scripps Research Institute (TSRI) have created detailed “fingerprints” of a class of surface receptors that have proven highly useful for drug development.  These detailed “fingerprints” show the surprising complexity of how these receptors activate their binding partners to produce a wide range of signalingRead more
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Dec 03,2015
Reasons Why Blocking microRNAs in Triple Negative Breast Cancer Is Difficult
    While a triple negative score is hardly ever a good thing, for breast cancer it is especially troubling. Triple-negative breast cancer (TNBC) refers to a disease scenario where the cancer cells do not express the genes for estrogen, progesterone, or HER2/neu receptors simultaneously—making this cancer particularly aggressive and difficult to treat as most chemotherapies targetRead more
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Reasons Why Blocking microRNAs in Triple Negative Breast Cancer Is Difficult
Dec 02,2015
Scientists Overcome Key CRISPR Cas9 Genome Editing Hurdle
    Researchers have engineered changes to the revolutionary CRISPR-Cas9 genome editing system that significantly cut down on ‘off-target’ editing errors. The refined technique addresses one of the major technical issues in the use of genome editing.  The CRISPR-Cas9 gene-editing system has been known to be overzealous, unwilling to call it quits after cutting its target site.Read more
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Dec 02,2015
Swimming Devices Could Deliver Drugs Inside the Body
Engineers at the University of Sheffield have discovered that tiny spherical bead-like devices can be guided by physical structures while swimming inside fluids. This opens up a wealth of future possibilities, such as using structures in the body to guide drug delivery, or cracks in rocks to direct environmental clean-up and exploration. These devices, whichRead more
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Dec 02,2015
Suppressing Aging Genes Extends Life Spans
    Youth, Maturity and old age: each stage in physiological aging is characterized by different patterns of gene expression, which complicates the search for "aging genes.” To deal with this complication, scientists centered at ETH Zurich compared aging-related patterns in gene expression in young, mature, and old model organisms—nematodes, zebrafish, and mice. By studying gene expressionRead more
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