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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Dec 15,2015
The Periodic Table of Proteins
Researchers have devised a periodic table of protein complexes, making it easier to visualize, understand and predict how proteins combine to drive biological processes. A new 'periodic table' of protein complexes, devised by an interdisciplinary team of researchers, provides a unified way to classify and visualize protein complexes, which drive a huge range of biologicalRead more
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Dec 15,2015
3D Human Genome Map Reveals Relationship between Mutations and Disease Development
    A map has been created of the DNA loops that comprise the three dimensional (3D) structure of the human genome and contribute to gene regulation in human embryonic stem cells by Scientists at the Whitehead Institute.  The location of genes and regulatory elements within this chromosomal framework will help scientists better navigate their genomic research,Read more
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Dec 14,2015
Using Big Data to Combat Flu
SBP has helped lead an international team of academic and pharmaceutical scientists that have tapped into publically available large-scale 'Omics' databases to identify new targets to treat influenza — the virus that causes annual epidemics and occasional pandemics. The study, published in Cell Host and Microbe, reflects a breakthrough approach using advanced computational designs toRead more
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Dec 14,2015
New Method Profiles Microbe Structure in the Search for Novel Antibiotics
    Traditional methods scientists have employed while on the hunt for better antimicrobial compounds have proven effective, yet extremely time-consuming and inefficient, often yielding only a few candidate compounds to take further into clinical studies. However now, researchers at UC San Diego have developed a method they believe will help identify and characterize new antibiotics, asRead more
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New Method Profiles Microbe Structure in the Search for Novel Antibiotics
Dec 11,2015
TET Proteins Shown to Play Key Role in Preventing Genome Instability
    Scientists at the La Jolla Institute for Allergy and Immunology say they have demonstrated that TET (ten-eleven translocation) proteins collectively constitute a major class of tumor suppressors and are required to maintain genome stability. Their study ("Acute loss of TET function results in aggressive myeloid cancer”), published in Nature Communications, shows that mice lacking bothRead more
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Dec 11,2015
Key Biological Markers for Psychotic Disorders Identified
    Researchers at the University of Georgia have identified several biological markers enabling greater precision in classifying mental disorders.  They believe their study (“Identification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers”), published in the American Journal of Psychiatry, may one day lead to improved diagnostics and treatments for those suffering from mental illness.       Despite advancesRead more
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Dec 10,2015
Enzyme Involved in Cell Division Play a Role in Inflammation
    UT Southwestern Medical Center and California researchers today provide the first report that an enzyme previously known solely for its role in cell division also acts as an on-off switch in the innate immune system—the body’s first defense against infection.       The identification of the NEK7 enzyme’s switch-like activity in immunity could lead to newRead more
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Dec 10,2015
Study Suggests New Way to Help the Immune System Battle Parasite
    African sleeping sickness, caused by the parasite Trypanosoma brucei, is transmitted by the tsetse fly and is fatal if left untreated. New research reveals a method to manipulate trypanosomes in the mammalian bloodstream to acquire fly stage characteristics. The findings suggest that inhibiting specific proteins can ‘trick’ the parasite into differentiating to a different stageRead more
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Dec 09,2015
Side Pocket of Nuclear Receptor Could Cue Up New Drugs
    Drug development is like a game of molecular billiards in which one must sink drugs into receptors. In the case of nuclear receptors, which are targeted by about 13% of all available pharmaceuticals, the game can be particularly challenging. It has been 50 years since an effective means of binding a novel site on aRead more
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Side Pocket of Nuclear Receptor Could Cue Up New Drugs
Dec 09,2015
Aging Stem Cells Provide Clues into Tumor Development
    Scientists at the University of Oregon (UO) have recently uncovered molecular events experienced by stem cells as they age, which could provide new pathway toward the discovery of novel therapies for cancer and neurological disorders. The researchers noticed that these changes arise in Drosophila during the development of the central nervous and at that timeRead more
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