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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Jan 05,2016
Vitamin D May Benefit Multiple Sclerosis Patients
    Taking a high dose of vitamin D3 is safe for people with multiple sclerosis and may help regulate the body’s hyperactive immune response, according to a pilot study published by Johns Hopkins physicians in the Dec. 30 online issue of Neurology, the medical journal of the American Academy of Neurology.     “These results are exciting, asRead more
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Jan 05,2016
Early Life Exercise Alters Gut Microbes
    The human gut harbors a teeming menagerie of over 100 trillion microorganisms, and researchers at the University of Colorado Boulder have discovered that exercising early in life can alter that microbial community for the better, promoting healthier brain and metabolic activity over the course of a lifetime.     “Exercise affects many aspects of health, both metabolicRead more
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Jan 04,2016
Cell Free Protein Synthesis is Potential Lifesaver
    Lives of soldiers and others injured in remote locations could be saved with a cell-free protein synthesis system developed at the Department of Energy's Oak Ridge National Laboratory.       The device, a creation of a team led by Andrea Timm, Ph.D., and Scott Retterer, Ph.D., of the lab's biosciences division, uses microfabricated bioreactors to facilitate theRead more
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Jan 04,2016
Community Acquired Cancer a Threat to Endangered Species
    Cancer is difficult enough to treat without being contagious, but Tasmanian devil populations are being faced with just that danger. A paper released by Proceedings of the National Academy of Sciences ("A second transmissible cancer in Tasmanian devils”)—coauthored by Ruth Pye, Ph.D., and senior professor Gregory Woods from the Menzies Institute for Medical Research—suggests thatRead more
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Dec 31,2015
Toxic ALS Protein Aggregate Structure Uncovered, Raises Hope for Drug Discovery
    A little over twenty years ago scientists discovered that a mutation in the gene that codes for superoxide dismutase (SOD1) was strongly linked to plaques found in amyotrophic lateral sclerosis (ALS)—also known as Lou Gehrig's disease—neuronal tissue and motor neuron death.       In the subsequent years since that seminal finding, researchers have significantly advanced theirRead more
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Toxic ALS Protein Aggregate Structure Uncovered, Raises Hope for Drug Discovery
Dec 31,2015
Novel Technique May Lead to Insights on Synaptic Activity in Learning and Disease
    Scientists at Carnegie Mellon University reportedly have developed a new approach to broadly survey learning-related changes in synapse properties. In a study ("Unbiased, High-Throughput Electron Microscopy Analysis of Experience-Dependent Synaptic Changes in the Neocortex”) published in The Journal of Neuroscience, the researchers used machine-learning algorithms to analyze thousands of images from the cerebral cortex. ThisRead more
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Dec 30,2015
Inflammatory Response to Malaria Infection Sabotages Immune System Protection
    Malaria parasites cause an inflammatory reaction that sabotages our body's ability to protect itself against the deadly disease, scientists have found for the first time.     The finding opens up the possibility of improving malaria vaccines by boosting key immune cells needed for long-lasting immunity. This could even include vaccines that have previously been ineffective inRead more
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Inflammatory Response to Malaria Infection Sabotages Immune System Protection
Dec 30,2015
A Novel Gene Safeguards Chromosome Could Play a Role in Cancer
    Molecular biologists at UT Southwestern Medical Center have identified a gene called NORAD that helps maintain the proper number of chromosomes in cells, and that when inactivated, causes the number of chromosomes in a cell to become unstable, a key feature of cancer cells.     Previously, genes that encode the recipe for making proteins have been implicatedRead more
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Dec 29,2015
Liver Hormone Regulates Sweet & Alcohol Preferences
    A hormone found in the liver has the ability to reduce sweet and alcohol cravings in mammals, a recent study found.     UT Southwestern Medical Center researchers found the hormone, fibroblast growth factor 21, works through the brain’s reward system to weaken cravings. It is induced in the body by extreme cold temperatures, sudden changes inRead more
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Dec 29,2015
Gene Switch Controlled Kinetically, Not Thermodynamically
    The regulatory elements known as genetic switches are usually understood in terms of thermodynamics. But thermodynamics, as a way of explaining physical processes, gives us just half the picture—and not necessarily the half that interests us. The other half is about kinetics. Essentially, thermodynamics is all about the "if” of a process, whether or notRead more
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