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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Feb 18,2016
Visualizing a Parasite Crossing the Blood Brain Barrier
    An estimated 30 percent of the world's population is chronically infected with the parasite Toxoplasma gondii. Most people live with the infection without noticeable effect, but it can be life-threatening for people with suppressed immune systems, such as people on cancer therapies or who have HIV/AIDS. Pregnant women can also pass an infection to theirRead more
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Feb 18,2016
Gene Linked to Response of Patients to Infectious Diseases
Scientists led by a group in the Center for Vascular Biology Research (CVBR) at Beth Israel Deaconess Medical Center (BIDMC) have shown that variations in the Tie2 gene, which is expressed on the inner surface of blood vessels, play an important role in patient responses to infectious diseases. The new study ("Gene control of TieRead more
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Gene Linked to Response of Patients to Infectious Diseases
Feb 17,2016
Lyme Diseases May Be Diagnosable via Transcriptome Signature
    Lyme disease is critical to detect at an early stage in order to prevent complications like, "arthritis, meningitis, facial palsy, and, in rare cases, myocarditis, or damage to heart muscle leading to sudden death”. However, researchers know that lyme can hide during the window period of infection before a detectable antibody response. So, scientists atRead more
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Feb 17,2016
Gene Previously Found in Brain Is Important Driver of Breast Cancer
When breast cancer becomes advanced and spreads to other organs, patient survival is drastically reduced, prompting the need to explore the genes that may cause tumor cells to metastasize.  Now, researchers from The Wistar Institute have shown that one gene that was once thought only to be found in the brain is also expressed inRead more
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Gene Previously Found in Brain Is Important Driver of Breast Cancer
Feb 16,2016
Researchers Create Compound That Combats Drug Resistant Malaria Parasites
    With media attention recently focused on the spread of the Zika virus, it's easy to forget about the mosquito-borne disease that has been credited with killing one out of every two people who have ever lived—malaria.  Malaria, one of the world's most devastating infectious diseases, exacts a yearly toll of more than 400,000 deaths, mostlyRead more
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Feb 16,2016
Biomolecular Structure Emerges from the Crystallographic Shadows
    In keeping with the adage, "If life gives you lemons, make lemonade,” an international team of scientists has shown that if X-crystallography relies on low-quality crystals, it can still derive high-quality structural information. In fact, resolutions can be achieved that surpass the Bragg diffraction limit.     The key, it turns out, is to make the mostRead more
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Feb 15,2016
Research Progress on Pharmacokinetics of Traditional Chinese Medicine
At present, the research on the pharmacokinetics of traditional Chinese medicine is still in the exploratory stage. Since the 1980s, the pharmacokinetics of traditional Chinese medicine has been greatly developed. This article reviews the pharmacokinetic research progress of some clinically commonly used active ingredients of traditional Chinese medicine. Starting from the characteristics and research statusRead more
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Research Progress on Pharmacokinetics of Traditional Chinese Medicine
Feb 12,2016
Clarified Role of Molecule Linked to Tumors Opens Door to New Cancer Therapies
    Researchers at the University of Liverpool have described the step-by-step creation of an important naturally occurring chemical in the body that plays a role in some cancers. S-Adenosylmethionine (SAMe) is a major methyl donor that is produced by the highly conserved Methionine Adenosyltransferase (MAT) family of enzymes.     Tight regulation of the level of SAMe isRead more
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Feb 12,2016
Team Genetically Maps Lethal Strains of E. coli
    Scientists at the University of Maryland, School of Medicine (UM SOM) say they have for the first time determined the genetic makeup of various strains of E. coli, which every year kill hundreds of thousands of people around the world. Their paper, which appears in a recent issue of Nature Microbiology, analyzed the DNA ofRead more
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Team Genetically Maps Lethal Strains of E. coli
Feb 11,2016
Possible Marker for Recurring HPV Linked Oropharyngeal Cancers
    A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at The Johns Hopkins University.     The National Cancer Institute estimates that HPVRead more
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