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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Mar 29,2016
RNA Bacteriophages May Open New Path to Fighting Antibiotic Resistant Infections
    Scientists at Washington University School of Medicine in St. Louis report that bacteriophages made of RNA likely play a much larger role in shaping the bacterial makeup of worldwide habitats than previously recognized. Their study ("Hyperexpansion of RNA Bacteriophage Diversity”), published in PLOS Biology, identified 122 new types of RNA bacteriophages in diverse ecological niches,Read more
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RNA Bacteriophages May Open New Path to Fighting Antibiotic Resistant Infections
Mar 29,2016
Protein Consolidates Promoter Beachhead in Advance of Full Scale Transcription
    The expression of a gene may be likened to a seaborne invasion. Both are logistically complex operations that are hard to follow. Both involve arriving at the right landing site, establishing a beachhead, and only then staging a mechanized advance.     Beyond these generalities are transcriptional details that have been obscured by a biochemical fog ofRead more
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Protein Consolidates Promoter Beachhead in Advance of Full Scale Transcription
Mar 28,2016
Devising an In Vitro Cell Surface Model
    Scientists have long been fascinated by the dichotomy that constitutes the cell surface: On one hand it is dynamically fluid, because it is dotted with diverse amounts of proteins, lipids, and carbohydrates. Yet the cell surface also acts as a stalwart rampart against the extracellular environment—setting up checkpoints that selectively allow entrance to molecules theRead more
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Devising an In Vitro Cell Surface Model
Mar 28,2016
Genetically Modified Maggots Helps Wounds Heal Faster
    Researchers working with genetically engineered maggots have made an exciting discovery that could change how we treat wounds. The team, comprised of scientists from NC State and Massey University in New Zealand, has created a strain of green bottle fly (Lucilia sericata) larvae capable of producing a human growth factor in detectable amounts. This growthRead more
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Genetically Modified Maggots Helps Wounds Heal Faster
Mar 25,2016
New Study Offers Insight into Extent of PKU Effect on Brain
    At birth, children are screened for an array of genetic diseases that may quickly present symptoms and be potentially life threatening. One such rare disorder is phenylketonuria (PKU), a metabolic condition in which the body cannot convert the amino acid phenylalanine into tyrosine, a precursor of dopamine and other important neurotransmitters. PKU is hallmarked byRead more
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Mar 25,2016
RNA May Surpass DNA in Precision Medicine
    It's not an either/or situation. Both DNA sequencing and RNA sequencing hold clinical promise—diagnostically, prognostically, and therapeutically. It must be said, however, that RNA sequencing reflects the dynamic nature of gene expression, shifting with the vagaries of health and disease. Also, RNA sequencing captures more biochemical complexity, in the sense that it allows for theRead more
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Mar 24,2016
Scientists Remove HIV from Human T Cells
    Scientists edited HIV-1 DNA out of the genome of human immune cells, preventing virus replication and reinfection of the cleared cells.     Using the CRISPR/Cas9 gene editing technique, scientists at Temple University eliminated HIV-1 DNA from T cell genomes in lab experiments, and prevented reinfection after the cells were re-exposed to the virus, they report inRead more
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Mar 24,2016
New Biomarker Identified as Cause of Breast Cancer and Early Indicator
    Researchers at the Medical College of Georgia and Georgia Cancer Center within Augusta University have identified a gene, previously known for its role in DNA repair pathways, which they describe as being a cause of breast cancer. However, due the GT198 gene's newly identified role in carcinogenesis, it has a strong potential both as aRead more
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Mar 23,2016
Dengue Vaccine Shows Promising Results in Clinical Trial
    The dengue virus is the most common mosquito-borne viral infection in the world, infecting nearly 400 million people annually. At its most severe, the flu-like disease can be fatal.  A clinical trial in which volunteers were infected with dengue virus 6 months after receiving either an experimental dengue vaccine developed by NIH scientists or aRead more
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Mar 23,2016
Removing Epigenetic Post It Notes Returns Stem Cells to Unprimed State
    A drug originally intended to treat leukemia has an unexpected power. It can reverse stem cell development, converting primed pluripotent stem cells to naïve pluripotent stem cells. The drug, called MM-401, effectively removes epigenetic markers from histones, depriving the cell's DNA-reading machinery of indications of where to start reading. Stripped of its accumulated “Post-it notes,”Read more
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