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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Apr 13,2016
Sequence and Epigenetic Factors Determine Overall DNA Structure
    The traditionally held hypothesis about the highly ordered organization of DNA describes the interaction of various proteins with DNA sequences to mediate the dynamic structure of the molecule. However, recent evidence has emerged that stretches of homologous DNA sequences can associate preferentially with one another, even in the absence of proteins.     Researchers at the UniversityRead more
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Sequence and Epigenetic Factors Determine Overall DNA Structure
Apr 12,2016
Nanotubes Could Boost Genetic Engineering
    Researchers have developed a new and highly efficient method for gene transfer. The technique, which involves culturing and transfecting cells with genetic material on an array of carbon nanotubes, reportedly overcomes the limitations of other gene editing technologies.     The device, which is described in a study (“High-Efficiency Gene Transfection of Cells through Carbon Nanotube Arrays”) publishedRead more
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Apr 12,2016
Lipids Found Critical to Breast Cancer Cell Proliferation
Scientists in Spain report finding that breast cancer cells need to take up lipids from the extracellular environment so that they can continue to proliferate. The main protein involved in this process is LIPG, an enzyme found in the cell membrane and without which tumor cell growth is arrested. Analyses of more than 500 clinicalRead more
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Lipids Found Critical to Breast Cancer Cell Proliferation
Apr 11,2016
Fleeting Membrane Raft Domains Finally Spotted
    About ten years ago, a self-avowed "lipid raft” skeptic referred to the membrane subcompartments as "now you see them, now you don't” entities. Actually, he was trying to draw attention to the various shifts in the definitions of lipid rafts, or raft domains, sections of the cell membrane that are said to consist of specialRead more
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Apr 11,2016
New Stem Cell Treatment Could Repair Any Tissue in the Body
    Stem cell therapies capable of regenerating any human tissue damaged by injury, disease or ageing could be available within a few years.  The repair system, similar to the method used by salamanders to regenerate limbs, could be used to repair everything from spinal discs to bone fractures, and has the potential to transform current treatmentRead more
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Apr 08,2016
Seeing Cell to Cell Differences to Explain Symptoms of Rare Genetic Disorders
Every cell in the body has two genomes, one from the mother and one from the father. Until now, researchers have lacked the tools to examine — in a single cell –the exact readout from each genome to make RNA. Scientists at the University of Pennsylvania Perelman School of Medicine and the Children's Hospital ofRead more
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Seeing Cell to Cell Differences to Explain Symptoms of Rare Genetic Disorders
Apr 08,2016
Novel Technology Allows Assessment of Drug Induced Mitochondrial Damage
Mitochondrial dysfunction plays a critical role in the development of chemical and pharmaceutical toxicity. However, current methods to evaluate mitochondrial activity still rely on traditional tests called endpoint assays, which provide limited prognostic information.       Scientists, however, from The Hebrew University of Jerusalem have described a new generation of Liver-on-Chip devices, in which the researchersRead more
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Novel Technology Allows Assessment of Drug Induced Mitochondrial Damage
Apr 07,2016
Biomarker Linked to Rapid Onset Diabetic Retinopathy
    Scientists at the Massachusetts Eye and Ear and Schepens Eye Research Institute say they have found an association between a defective myogenic response (the regulatory increase or decrease in blood pressure to keep blood flow within the vessels of the retina constant) and early, accelerated development of retinopathy in patients with type 1 diabetes. TheseRead more
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Biomarker Linked to Rapid Onset Diabetic Retinopathy
Apr 06,2016
Vaccine Shows Cancer Cells May Succumb to Induced Necroptosis, Not Just Apoptosis
    Some of the most promising experimental cancer therapies have been exploiting immunogenic cell death, a means of heightening the immune system's ability to attack tumors. To date, immunogenic cell death has been induced by means of apoptosis, a kind of programmed cell death. Meanwhile, another cell death mechanism, necroptosis, has remained relatively unexplored. But nowRead more
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Apr 06,2016
Study Discovers Link Between Celiac Disease Risk and a Noncoding RNA
    In the last several years, consumers have become increasingly aware of gluten—a protein found in cereal grains, wheat, rye, and barley—and its association with intestinal inflammation, specifically due to celiac disease (CD), an autoimmune digestive disorder in which genetically predisposed individuals develop an immune response to gluten. While gluten-free products are currently all the rage,Read more
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