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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
Apr 27,2016
Genetic Approach May Lead to New Treatments for Digestive Diseases
    Scientists at the University of Massachusetts Medical School (UMMS) say they have identified a new molecular pathway critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system. This finding, based on studying calcium ion-controlled pathways in mice, may lead to new treatments for a host of digestive disorders,Read more
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Genetic Approach May Lead to New Treatments for Digestive Diseases
Apr 27,2016
Medicilon in Situ Hybridization Technology Service
Definition: in situ hybridization (insituhybridization) is a kind of molecular hybridization, which is a kind of hybridization of the labeled probe directly to the nucleic acid to be tested in the tissue or cell, and the principle of immunocytochemistry uses a suitable detection system to target A method for precise and quantitative positioning of nucleicRead more
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Medicilon in Situ Hybridization Technology Service
Apr 27,2016
Fluorescence in Situ Hybridization
Fluorescence in situ hybridization can be used to detect specific DNA or RNA in cells to determine the expression and location of specific genes. It can also be used to detect chromosomal changes in tumors or other diseases. Fluorescence in situ hybridization FISH (fluorescence in situ hybridization) technology is a new positioning technology developed inRead more
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Fluorescence in Situ Hybridization
Apr 26,2016
Kidney Function Protein Exhibits Role in Nervous System
    Scientists at the University of Louisville have discovered that a protein previously known for its role in kidney function also plays a significant role in the nervous system. In an article ("The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity”) in the April issue of the Journal of Neuroscience, they show that the adaptorRead more
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Kidney Function Protein Exhibits Role in Nervous System
Apr 26,2016
Findings Point to a Novel Approach to the Treatment of Diabetes
    Blocking the hormone that raises sugar levels in the blood could increase insulin levels while keeping blood sugar levels down. A new study in mice (“Blockade of Glucagon Signaling Prevents or Reverses Diabetes Onset Only If Residual ß-Cells Persist”), to be published in eLife, points to a novel way to treat diabetes, but only in someRead more
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Apr 25,2016
Novel Epigenetic Drug Therapeutics Revealed
    As the 2016 American Association for Cancer Research meeting begins to downshift toward a close, the presentation sessions certainly did not suffer from a lack of enthusiasm from attendees or high-quality research from presenters. Of particular note was a major symposium that discussed next-generation epigenetic therapeutics.       In the past several years, there have beenRead more
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Novel Epigenetic Drug Therapeutics Revealed
Apr 25,2016
Laser Driven Protein Transport Reveals Epigenetic Dynamics
    A new technique for probing the functions of genes and proteins works by enabling the laser-directed movement of proteins from one cellular location to another. The technique, a form of optogenetics, has already been used to export an epigenetically active protein from the nucleus. Soon after this relocation was accomplished, a rapid fading of particularRead more
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Laser Driven Protein Transport Reveals Epigenetic Dynamics
Apr 21,2016
CRISPR as a Screening Tool for Drug Targets
Once again the quality of research presented at the annual American Association for Cancer Research (AACR) meeting transcends excellence. Researchers from around the globe have descended on the city of New Orleans to exchange ideas that they all hope will lead them down the path toward the next impactful cancer therapeutic. There is certainly noRead more
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CRISPR as a Screening Tool for Drug Targets
Apr 21,2016
Computer Algorithm Helps Characterize Cancerous Genomic Variations
Scientists at the University of California San Diego School of Medicine and the Broad Institute say they have developed a new computer algorithm—REVEALER—to better characterize the functional context of genomic variations in cancer. The tool, described in a paper ("Characterizing Genomic Alterations in Cancer by Complementary Functional Associations”) published in Nature Biotechnology, is designed toRead more
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Computer Algorithm Helps Characterize Cancerous Genomic Variations
Apr 20,2016
Improvement of Gene Editing for Immunotherapy
    The gene-editing tool TALEN can be used to inactivate PD-1-mediated immunosuppression and enhance the efficacy of a type of immunotherapy called adoptive T-cell transfer against solid tumors, according to a preclinical study published in Cancer Research, a journal of the American Association for Cancer Research.  Some of the most impressive results were provided by aRead more
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Improvement of Gene Editing for Immunotherapy
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