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Hot information：
Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
May 11,2016
The Unique microRNAs of Naked Ape May Have Contributed to Human Evolution
    In the popular press, humans and other apes are said to share surprisingly large amounts of DNA. For example, human and chimpanzee DNA is supposed to be 98.8% the same. So why, readers are left to wonder, are humans so different from other apes? Readers usually have to content themselves with vague explanations—the small percentageRead more
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May 10,2016
Scientists Shed Light on Key Role of Innate Lymphoid Cells in the Immune Response
    Through the use of powerful genomic techniques, researchers at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) have found that the development of immune cells, called innate lymphoid cells (ILCs), gradually prepares these cells for rapid response to infection. This work, which appeared online in Cell, sheds light on the development andRead more
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Scientists Shed Light on Key Role of Innate Lymphoid Cells in the Immune Response
May 10,2016
Mechanism for Escaping Cellular Trojan Horse Detailed
Molecular troops can sneak past the cell's ramparts if they are tucked inside an endosome, but they can become trapped, unable to escape the endosome and roam the cytosol. The endosome, then, can be a tricky sort of Trojan horse. It needs the equivalent of better escape panels. Intent on designing a better Trojan horse,Read more
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Mechanism for Escaping Cellular Trojan Horse Detailed
May 09,2016
Human Embryo Grown in Lab
    Scientists based at The Rockefeller University have created an experimental system that models the implantation of a human embryo. The new system, an adaptation of one used to recapitulate the implantation of a mouse embryo, provides an attachment substrate, surrounds the blastocyst with just the right chemical environment, and provides scaffolding that accommodates the morphologicalRead more
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May 09,2016
Scientists Find Root Cause of Appetite Loss during Illness
    Loss of appetite during illness is a common and potentially debilitating phenomenon — in cancer patients, especially, it can even shorten lifespan.     Investigators at The Scripps Research Institute (TSRI) have discovered how an immune system molecule hijacks a brain circuit and reduces appetite during an illness. Their research points to potential targets for treating lossRead more
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May 06,2016
New Pancreatic Treatment Shows Promise
    Scientists say they have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis, pointing to a potential new treatment using drugs previously developed for atherosclerosis.       "We show for the first time that if you control the cholesterol metabolism you could reduce pancreatic cancer spread to other organs,” said Ji-Xin Cheng, Ph.D., aRead more
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New Pancreatic Treatment Shows Promise
May 06,2016
Scientists Double Number of Known Genetic Risk Factors for Endometrial Cancer
The strength of genome-wide association studies (GWAS) lies in their ability to identify new disease biomarkers through large-scale genomic comparisons of afflicted individuals and unaffected controls. Now, using this powerful technique, an international collaboration of researchers has identified five new gene regions that increase a woman's risk of developing endometrial cancer, one of the most common cancers to affect women, taking the number of known gene regions associated with the disease to nine.
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Scientists Double Number of Known Genetic Risk Factors for Endometrial Cancer
May 05,2016
Study Suggest Current Cancer Drug Discovery Method Is Flawed
    Understanding how cells respond and proliferate in the presence of anticancer compounds has been the foundation of drug discovery ideology for decades. Now, the primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers report May 2 in Nature Methods. The findings cast doubt on methods used by theRead more
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Study Suggest Current Cancer Drug Discovery Method Is Flawed
May 05,2016
Synaptic Pruning Discovery May Lead to New Therapies for Neuro Disorders
A research team led by scientists at SUNY Downstate Medical Center has identified a brain receptor that appears to initiate adolescent synaptic pruning, a process believed necessary for learning, but one that appears to go awry in both autism and schizophrenia.   Sheryl Smith, Ph.D., professor of physiology and pharmacology at SUNY Downstate, explained thatRead more
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May 04,2016
Researchers Chemically Alter Skin Cells into Heart and Brain Cells
    Cellular reprogramming of stem cells derived from one tissue type into a different vastly different tissue typically requires the labor-intensive use of external genes to modify and coax the existing genetic machinery down the desired path. Now, scientists at the Gladstone Institutes have established what they believe is a major breakthrough for stem cell research.Read more
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Researchers Chemically Alter Skin Cells into Heart and Brain Cells
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