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Top 10 Global CDMO Enterprises| The Meaning of IND, NDA and ANDA| Top 10 Global Clinical Research Organizations in 2021
May 25,2016
Sunscreen Gene May Guard Against Skin Cancer
Scientists at the University of Southern California (USC) say they've identified a so-called "sunscreen” gene that may help protect against skin cancer.  Melanoma—the deadliest form of skin cancer—has seen rates double over the last three decades, according to the CDC, causing scientists to be even more vigilant in their search to understand the underlying molecular mechanismsRead more
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Sunscreen Gene May Guard Against Skin Cancer
May 24,2016
Appetite of Biomimicry Stem Cells for Nano Labels
If they are to be evaluated properly, stem cells that are deployed clinically need to be labeled. Even better, stem cells need to internalize tracking labels that can be picked up by means of magnetic resonance imaging (MRI). Yet stem cells such as mesenchymal stem cells (MSCs) seem to object to force-feeding, at least inRead more
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May 24,2016
Killing MRSA with an Antarctic Sponge
    The exponential rise of antimicrobial resistance has sent researchers scrambling to identify novel compounds that can circumvent the microbial resistance mechanisms. This critical undertaking has caused many scientists to think outside the box and travel to extreme locations for new sources of antimicrobial compounds.     Scientists have isolated an extract from a sponge found in Antarctica,Read more
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May 23,2016
Researchers Develop Non Toxic Approach for Treating Cancers
A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami, Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers. The treatment approach is based on a combination therapy of the sugar 2-Deoxy-D-glucose (2-DG) and fenofibrate, a well-studied cholesterol medication. The study was publishedRead more
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May 23,2016
Comet Clues Lead to RNA World Revelations
    "The cosmos is within us,” said Carl Sagan. "We are made of star stuff.” Memorable words, but they don't explain how "star stuff”—pretty much all the chemical elements—could have come together in various ways to form life's chemical building blocks—proteins and nucleic acids. No doubt Sagan was aware that the story of chemical evolution stillRead more
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May 20,2016
Study Advances Understanding of Colon Cancer
    Inflammatory bowel disease (IBD), of which Crohn's disease and ulcerative colitis are the main types, is on the increase in the United States, affecting more than 1.6 million people and explaining perhaps the increase in advertisements offering treatments and cures. Another intestinal disease is colon cancer, a leading cause of death, which is linked toRead more
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Study Advances Understanding of Colon Cancer
May 20,2016
Blocking Know Cancer Driver Unexpectedly Reveals a New Tumor Promoting Pathway
    While investigating a potential therapeutic target for the ERK1 and 2 pathways, a widely expressed signaling molecule known to drive cancer growth in one third of patients with colorectal cancer, University of California San Diego School of Medicine researchers found that an alternative pathway immediately emerges when ERK1/2 is halted, thus allowing tumor cell proliferationRead more
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Blocking Know Cancer Driver Unexpectedly Reveals a New Tumor Promoting Pathway
May 19,2016
Stem Cell Factor Boosts Cardiovascular Protection
    Oct4, a gene essential to embryonic development, remains functional in adults, offering cardiovascular protection through the stabilization of atherosclerotic plaques. Essentially, Oct4 helps prevent heart attacks and strokes.       The finding is a surprise. While there had been hints that Oct4 could serve some function later in life, convincing evidence was lacking. Now that Oct4Read more
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Stem Cell Factor Boosts Cardiovascular Protection
May 19,2016
Anchors Provide Novel Way to Hijack Superbugs
Scientists at Monash University of Australia may have found a way to stop deadly bacteria from infecting patients. The discovery could lead to a whole new way of treating antibiotic-resistant "superbugs.” The researchers have uncovered what may be an Achilles heel on the bacteria cell membrane that could act as a potential novel drug target.Read more
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Anchors Provide Novel Way to Hijack Superbugs
May 18,2016
Altering the Microbiome Improves Stress Resistance and Coping Responses
    Injections of the soil bacterium Mycobacterium vaccae promote stress resilience and improve coping behaviors in mice, according to a new study led by researchers at University of California San Diego School of Medicine and University of Colorado Boulder. The researchers also found that M. vaccae prevented stress-induced colitis, a typical symptom of inflammatory bowel disease, suggesting that immunizationRead more
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Altering the Microbiome Improves Stress Resistance and Coping Responses